AChemS XL


Printable Program




April 17-20, 2018

Bonita Springs, FL


Wednesday, April 17, 2024


10:00 - 11:40 AMCalusa ABC
Understanding Odor Coding and Odor-Guided Behaviors in the Age of Team Science - PART 1: New Technologies and Data Integration

10:00
Determinism In Odor Receptor Choice
David Brann
Harvard University

10:25
How Do Class I Odorant Receptors Recognize Odorants?
Hiro Matsunami
Duke University

10:50
Restructuring Of Odor Responses Along Ethologically Important Axes
Tatyana Sharpee
Salk Institute

11:15
The Tango Toolkit For Circuit Tracing And Manipulation
Gilad Barnea
Brown University

11:40 - 12:40 PMLunch On Own
Lunch On Own

12:00 - 3:30 PMGreat Egret
AChemS Executive Committee Meeting (Invite Only)

12:40 - 2:20 PMCalusa ABC
Understanding Odor Coding and Odor-Guided Behaviors in the Age of Team Science - PART 2: Natural Behaviors and the Olfactory System

12:40
Revealing The Neural Encoding Of Odor Intensity
Beatrice Barra
New York University

1:05
Olfaction In Drosophila Through The Lens Of Natural Odors
Elizabeth Hong
Caltech

1:30
Neural Circuits For Working Memory And Evidence Integration During Olfactory Navigation
Kathy Nagel
New York University

1:55
Voluntary Use Of The Vomeronasal System During Freely Moving Behavior
Lisa Stowers
The Scripps Research Institute

2:20 - 2:35 PMCalusa Foyer
Coffee Break

2:35 - 3:50 PMCalusa ABC
Understanding Odor Coding and Odor-Guided Behaviors in the Age of Team Science - PART 3: Smelling in Time and Space

2:35
The Order Code
Alex Koulakov
Cold Spring Harbor

3:00
Untangling The Determinants Of Timing And Tuning In Early Odor Representations
Matt Wachowiak
University of Utah

3:25
Olfactory Object Representation In The Brain
Dima Rinberg
New York University

4:00 - 4:30 PMGreat Egret
AChemS 2024 Codefest

The goal of the AChemS 2024 Codefest is for you to apply your data analysis skills, learn from others, get feedback, explore others' work, and connect with the larger AChemS community. This year's Codefest will focus on data from a new Olfaction Challenge. We will provide starter code, orient you to the available data, and provide a team of teachers as support for working in both R and Python. We welcome coders of all skill levels and from any chemosensory system!


4:30 - 5:00 PMCalusa Terrace
Diversity Fellowship Meet and Greet

5:30 - 6:00 PMCalusa EFGH
Awards Ceremony

6:00 - 7:00 PMCalusa EFGH
Keynote Lecture

Pheromone Communication In Ants
Daniel Kronauer
The Rockefeller University

7:00 - 9:00 PMWaterfall Pool Deck
Welcome Banquet (Ticket Required)






Thursday, April 18, 2024


7:30 - 9:00 AMEstero Foyer
Breakfast With Industry

CARGILL
Please join us at our breakfast table to share our excitement about career opportunities at Cargill. Sitting at the heart of the supply chain, we are focused on nourishing the world in a safe, responsible, and sustainable way. Cargill's technical professionals around the world have high impact as we partner with farmers and customers globally to source, make and deliver products that are vital for living.

COCA-COLA COMPANY
Our company purpose is to refresh the world and make a difference. We aim to create beverages with great taste that give consumers more choices. We are investing in R&D to find new approaches to continue delivering great-tasting beverages with zero or reduced levels of sugar. Join us at our table for a conversation on how we can collaborate to meet our shared goals.

W2O FOOD INNOVATION
Please stop by the W2O Food Innovation table. Tell me what you can do and want to do, and I will try to relate you to what the food industry needs. Ask me anything about NeuroFoodScience, that is, the application of Neuroscience in Food Science.




8:00 - 10:00 AMEstero Ballroom
Poster Session I

P100
Gaba Release From Palatal Taste Buds After Stimulation With Sweeteners
Yuryanni A. Rodriguez1, Gennady Dvoryanchikov 1, Stephen D. Roper1,2, Nirupa Chaudhari1,2
1Dept. of Physiology and Biophysics Univ. of Miami Miller School of Medicine, Miami, FL, United States, 2Dept. of Otolaryngology Univ. of Miami Miller School of Medicine, Miami, FL, United States

P102
Gustatory Nerve Fiber Innervation Drives Presynaptic Specialization Accumulation In Taste Receptor Cells.
Shannon M. Landon, Emily R. Holder, Laura Pinto, Saima Humayun, Lindsey J. Macpherson
University of Texas at San Antonio, San Antonio, TX, United States

P104
Application Of Expansion Microscopy To Study Taste
Kang-Hoon Kim, Emma Larsson, Minliang Zhou, Hong Wang
Monell Chemical Senses Center, Philadelphia, PA, United States

P108
Molecular Identification Of The Remarkable Diversity Of Geniculate Ganglion Sensory Neurons And Glia
Debarghya Dutta Banik, Tao Tang, Brian A. Pierchala
Indiana University School of Medicine, Indianapolis, IN, United States

P110
Neuronal Regulation Of Adult Taste Stem Cells
Jiang Xu1, Alan Moreira de Araujo1, Ranhui Xi1, Xiaoli Lin1, Chanyi Lu1, Kurt Hankenson2, Robert F Margolskee1, Ichiro Matsumoto1, Guillaume de Lartigue1, Myunghwan Choi3, Peihua Jiang1
1Monell Chemical Senses Center, Philadelphia, PA, United States, 2University of Michigan, Ann Arbor, MI, United States, 3School of Biological Sciences, Seoul National University, Seoul , Korea

P112
A Novel Cell Model For Bitter Taste Threshold Prediction Based On Interleukin-6 Release In Human Gingival Fibroblasts
Johanna Tiroch1,5, Andreas Dunkel2, Sonja Sterneder1,2,5, Sofie Zehentner1,5, Maik Behrens2, Antonella DiPizio2, Jakob Ley3, Barbara Lieder1, Veronika Somoza1,2,4
1University of Vienna, Faculty of Chemistry, Vienna, Austria, 2Leibniz-Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany, 3Symrise AG, Holzminden, Germany, 4Technical University of Munich, School of Life Sciences, Freising, Germany, 5University of Vienna Doctoral School in Chemistry, Vienna, Austria

P114
Bitter Peptides Derived From Gastric Digestion Of Sweet-Tasting Thaumatin Ameliorate H. Pylori Induced Pro-Inflammatory Il-17A Release Via Bitter Taste Receptor Tas2R16
Phil Richter1,2, Karin Sebald2, Konrad Fischer3, Angelika Schnieke3, Malek Jlilati2, Verena Mittermeier-Kleßinger4, Veronika Somoza2,5,6
1TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany, 2Leibniz Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany, 3Chair of Livestock Biotechnology, TUM School of Life Sciences, Technical University of Munich, Freising, Germany, 4Chair of Food Chemistry and Molecular Sensory Science, Technical University of Munich, Freising, Germany, 5Chair of Nutritional Systems Biology, TUM School of Life Sciences, Technical University of Munich, Freising, Germany, 6Department of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria

P116
The Addition Of Some But Not All Amino Acids To Soil Increases The Feeding Rate Of The Earthworm, Dendrobaena Veneta.
Jonathan G Mebrahtu1, Folashaye E Araromi1, Ameena A Mohassib1, Laura Ortega-Damian1, Rebeca V Rodriguez1, Tania C Romero1, Renalison Farias-Pereira1, Michael J Rizzo2, Cecil J Saunders1
1Kean University, Union, NJ, United States, 2Wake Forest Unviersity, Winston-Salem, NC, United States

P118
Affective Odors Modulate Neural Processing Of Emotional Visual Stimuli
Chloe E. Johnson, Colin B. Bowyer, Danielle N. Jones, Austin C. Pauley, James S. Brown, Adam K. Dewan, Christopher J. Patrick
Florida State University, Tallahassee, FL, United States

P120
Predicting Intensity Interactions In Odor Mixtures
Robert Pellegrino1, Matt Andres1, Vijay Singh2, Josh Nsubuga1, Khristina Samoilova3, Cyrille Mascart3, Alex Koulakov3, Joel Mainland1
1Monell Chemical Senses Center, Philadelphia, PA, United States, 2Department of Physics, NC A&T State University, Greensboro, NC, United States, 3Cold Spring Harbor Laboratory, Cold Springs Harbor, NY, United States

P122
Obsessive-Compulsive Behavioral Traits Do Not Predict Odor Awareness And Olfactory Hyperreactivity In The General Population: Results Of A Representative National Survey In The Czech Republic
Lenka Martinec Novakova, Dagmar Schwambergova, Jan Havlicek, Iveta Hocko Fajnerova
National Institute of Mental Health, Klecany, Czech Republic

P124
Zona Pellucida Like Domain Containing 2 Is Involved In The Stimulation-Dependent Neurogenesis Of Specific Olfactory Sensory Neuron Subtypes In Mice
Karlin E Rufenacht, Kawsar Hossain, Amanda Stenzel, Madeline Smith, Stephen Santoro
Department of Pediatrics, Section of Developmental Biology, University of Colorado Anschutz Medical Campus , Aurora, CO, United States

P126
Asymmetric Histone Inheritance Patterns In Mammalian Olfactory Horizontal Stem Cells
Binbin Ma1, 2, Guanghui Yang1, 2, Jonathan Yao2, Gabriel Manske3, Sue Hammoud3, Xin Chen1, 2, Haiqing Zhao2
1Howard Hughes Medical Institute, Department of Biology, Johns Hopkins University, Baltimore, MD, United States, 2Department of Biology, Johns Hopkins University. , Baltimore, MD, United States, 3Department of Urology, University of Michigan., Ann Arbor, MI, United States

P128
The Role Of Evoked Activity In The Survival And Functional Integration Of Newborn Olfactory Sensory Neurons
Kendall A Curtis, Sarah PR Berg, Claire EJ Cheetham
University of Pittsburgh, Pittburgh, PA, United States

P130
Hedgehog Signaling Regulation Of Embryonic Lingual Muscles Differentiation
Gabrielle C. Audu1, Sally Y. Rohan2, Archana Kumari1
1Department of Cell Biology and Neuroscience, Rowan-Virtua School of Osteopathic Medicine, 2 PBL, Rowan-Virtua School of Osteopathic Medicine

P132
The Endoplasmic Reticulum Protein Canopy1, Plays A Key Role In Vomeronasal Homeostasis And Neuronal Connectivity
Nicholas A. Mathias1,2, Paolo E. Forni1,2,3
1Biological Sciences, University at Albany, Albany, NY, United States, 2The RNA Institute, University at Albany, Albany, NY, United States, 3The Center for Neuroscience Research, Albany, NY, United States

P134
The Psychophysical Analysis Of &Ldquo;Maple&Rdquo; And &Ldquo;Buddy&Rdquo; Aromas In Maple Syrup Products When Exposed To Light And Elevated Temperatures During Storage
Yao Jiang, Alina N. Stelick, Patti de Cruilles, Hanfei Liu, Leto Solla, Catherine Belisle, Aaron Wightman, Robin Dando, Terry E Acree
Cornell University, Ithaca, NY, United States

P136
Integration Of A Gustometer And A Sniff Olfactometer Into The Same Psychopy Program To Measure The Effects Of Taste Stimulation On Odor Perception
Tiffany Hsu, Yao Jiang, Leto Solla, Jing Wu, Milan Poland, Robin Dando, Terry Acree
Cornell University, Ithaca, NY, United States

P138
Comparing Odor Perception Across Humans And Mice
Elizabeth Hamel1, Robert Pellegrino1, Mebelyn Urena1, Sebastian Ceballo2, Saeed Karimimehr2, Khristina Samoilova3, Matt Andres1, Jenny Margolis1, Alexei Koulakov3, Dima Rinberg2, Joel Mainland1
1Monell Center, Philadelphia, PA, United States, 2New York University, New York City, NY, United States, 3Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, United States

P140
Bitter Taste Perception And Its Neuronal Underpinning
Tal Belity1, Anan Moran1,2
1Department of Neurobiology, School of Neurobiology, Biochemistry & Biophysics, The George S. Wise Faculty of Life Science, Tel-Aviv University, Tel Aviv, , 2Sagol School of Neuroscience, Tel-Aviv University, Tel Aviv,

P142
Behaviorally Relevant Features Of The Neural Code In Olfactory Bulb
Saeed Karimimehr1,2, Sebastian Ceballo1, Mursel Karadas1, Dmitry Rinberg1,2,3
1Neuroscience Institute, New York University Langone Health, New York, NY, United States, 2Center for Neural Science, New York University, New York, NY, United States, 3Department of Physics, New York University, New York, NY, United States

P144
Loss Of Smell And The Olfactory-Hippocampal Gamma Oscillation Changes In The Acceleration Of Alzheimer'S Disease Progression
Joseph A. Villanueva1,2, Maria A. Nagel2,3, Diego Restrepo1,2,4
1Department of Cell & Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 2Department of Neurology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 3Department of Ophthalmology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 4Neuroscience Graduate Program, University of Colorado Anschutz Medical Campus, Aurora, CO, United States

P146
Evolution Of Olfactory Sensitivity In The Mexican Cavefish
Evan Lloyd1, Alex Keene2, Kimberly A Hughes1, Douglas A Storace1
1Florida State University, Tallahassee, FL, United States, 2Texas A&M University, College Station, TX, United States

P148
Altered Odor-Mediated Social Behavior In A Model Of Fragile X Syndrome
Lucy C. Irvine2, Navarrete Marcela1, Joaquin De la Rosa1, Juan Zegers2, Ricardo C. Araneda2, Alexia Nunez-Parra1, Jorge Mpodozis1
1Department of Biology, University of Chile, Santiago, Chile, 2Department of Biology, University of Maryland, College Park, MD, United States

P150
&Shy;&Shy;The Superficial Tufted And Mitral Cell Output Neurons Of The Mouse Olfactory Bulb Have A Dual Role In Insulin Sensing.
Louis J. Kolling1, 2, Catherine Anne Marcinkiewcz1, Debra Ann Fadool2
1Department of Neuroscience & Pharmacology, University of Iowa, Carver College of Medicine, Iowa City, IA, United States, 2Program in Neuroscience & Institute of Molecular Biophysics, Florida State University, Tallahassee, FL, United States

P152
Effects Of Two Alzheimer&Rsquo;S Disease Risk Factors On Neuronal And Synaptic Properties In The Anterior Olfactory Nucleus Of Mice.
Xiaotao Jin, Meigeng Hu, Dan Zhao, Shaolin Liu
University of Georgia, Athens, GA, United States

P154
The Bitter Side Of Habitual Low-Calorie Sweetener (Lcs) Use: Exploring Associations With Lcs Consumption Patterns And Glucose Metabolism, Sweetness Perception, And Added Sugar Intake
Mariel Molina-Castro1, Clara Salame2, Blair Rowitz2,3, M. Yanina Pepino1,2,3
1Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 2Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 3Carle Illinois College of Medicine, Urbana, IL, United States

P156
Individual Differences In Cephalic Phase Insulin Release
Alexa J. Pullicin, Juyun Lim
Oregon State University, Corvallis, OR, United States

P158
Don Tucker Finalist: Taste And Smell Perception After Metabolic Surgery
Jessica G. Nicanor-Carreón1, Blair Rowitz1,2,3, M. Yanina Pepino1,4
1Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 2Carle Illinois College of Medicine, Urbana, IL, United States, 3Department of Surgery, Carle Foundation Hospital, Urbana, IL, United States, 4Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, IL, United States

P160
Achems Undergrad Finalist: Lower Perception Of Odors Intensity In Late Evening May Contribute To Poor Diet Intake In Evening Sleep Phenotypes
Surabhi Bhutani, Paige Sullivan, Victoria Esparza, Kyra Jensen, Matthew Woods, Katie Quis, Uduak George
San Diego State Unversity, San Diego, CA, United States

P162
Defining The Role Of Immature Olfactory Sensory Neurons In Olfaction
Jordan D. Gregory1, 2, Ryan S. Herzog1, 2, Claire E. Cheetham1
1Dept. of Neurobiology, University of Pittsburgh, Pittsburgh, PA, United States, 2Center for Neuroscience at the University of Pittsburgh, Pittsburgh, PA, United States

P164
Irhom2 Regulates The Olfactory Receptor Landscape
Hsiu-Yi Lu1, Stephanie Azzopardi2, Jane Salmon3, Carl Blobel3, Hiroaki Matsunami1
1Molecular Genetics and Microbiology, Duke University, Druham, NC, United States, 2Tri-I MD/PhD Program, Weill Cornell Medicine, Rockefeller Univ, Sloan-Kettering Institute, new york, NY, United States, 3Hospital for Special Surgery at Weill Cornell Medicine, new york, NY, United States

P166
Arl13B Controls Localization Of Pip2 In The Mouse Olfactory Cilia And Neuronal Functional Output.
Kirill Ukhanov1, Warren Green2, Chao Xie3, Jeffrey Martens1
1University of Virginia, Charlottesville, VA, United States, 2University of Florida, Gainesville, FL, United States, 3Nikon Canada, Toronto, ON, Canada

P168
Characterization Of Enhancer Motifs And Transcription Factors That Drive Trace Amine-Associated Receptor Gene Choice
Maddie Ratkowski1, Rya Muller1, Kyungho Seong1, David Brann2, Tatsuya Tsukahara2, Sandeep R. Datta2, Thomas Bozza1
1Department of Neurobiology, Northwestern University, Evanston, IL, United States, 2Department of Neurobiology, Harvard Medical School, Boston, MA, United States

P170
Flavors And Fragrances Can Modulate Gene Expression Via Epigenetic Changes
Anandasankar Ray, Rogelio Nunez-Flores, Sachiko Haga-Yamanaka
MCSB, University of California, Riverside, CA, United States

9:00 - 10:00 AMEstero Foyer
Coffee Break

10:00 - 12:00 PMCalusa EFGH
Chemosensory perception and eating behavior: from inborn variation through gut-brain circuit to COVID-19

Chair(s): Danielle Reed
10:00
Chemosensory Perception And Eating Behavior: From Inborn Variation Through Gut-Brain Circuits To Covid-19
Danielle Reed1, Joanne Cole2
1Monell Chemical Senses Center, Philadelphia, PA, United States, 2University of Colorado School of Medicine , Aurora, CO, United States

10:02
Savor The Flavor: When Covid-19 Silences The Palate
Sanne Boesveldt1, Elbrich M. Postma1,2, Birgit P.M. van Dijk1
1Division of Human Nutrition and Health, Wageningen University, Wageningen, Netherlands, 2Smell and Taste Center, ENT department, Hospital Gelderse Vallei, Ede, Netherlands

10:27
Insulin Modulates Excitatory Drive Of Pyramidal Neurons In The Posterior Piriform Cortex.
Vaibhav R. Konanur, Celine Sanluecha, Lindsay R. Vivona, Joseph D. Zak
University of Illinois at Chicago, Chicago, IL, United States

10:45
Influence Of Common Missense Variants In Chemosensory Receptor Genes On Food Preferences
Danielle Reed1, Liang-Dar Hwang2, Cailu Lin1, Paule Joseph3
1Monell Chemical Senses Center, Philadelphia, PA, United States, 2The University of Queensland, Brisbane, Australia, 3Section of Sensory Science and Metabolism (SenSMet), National Institute on Alcohol Abuse and Alcoholism & National Institute of Nursing Research, Bethesda, MD, United States

11:10
Gut Influences On Central Feeding Circuits
Amber L Alhadeff
Monell Chemical Senses Center, Philadelphia, PA, United States

11:35
Phenome-Wide Association Analysis Of Supertaster Gene Tas2R38 Reveals Novel Relationship With Bipolar Disorder And Kidney Function
Liang-Dar Hwang1,2, Amanda WY Lim2, Quimbe Dy1, Jue-Sheng Ong2, Caroline Brito Nunes1
1Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia, 2QIMR Berghofer Medical Research Institute, Brisbane, Australia

10:00 - 12:00 PMCalusa ABC
Chemosensory mechanisms that drive innate behavior

Chair(s): Lisa Stowers
10:00
How Does Vomeronasal Sensing Differ From Taste Or Olfaction?
Lisa Stowers
Scripps Research, La Jolla, CA, United States

10:02
Chemosensory Mechanisms That Drive Innate Behavior
Lisa Stowers
Scripps Research, La Jolla, CA, United States

10:20
A Modular Circuit Architecture Coordinates The Diversification Of Courtship Strategies In Drosophila
Rory T. Coleman1, Ianessa Morantte1, Gabriel T. Koreman1, Megan L. Cheng1, Yun Ding2, Vanessa Ruta1
1Rockefeller University and Howard Hughes Medical Institute , New York, NY, United States, 2University of Pennsylvania, Philadelphia, PA, United States

10:45
Instinctive Behavior Circuit Development Is Shaped By Chemosensory Input, Sex, And Function
Harris Kaplan1, Brandon Logeman1, Kai Zhang2,3, Celine Santiago4, David Ginty4, Bing Ren2, Catherine Dulac1
1Department of Molecular and Cellular Biology, Howard Hughes Medical Institute, Center for Brain Science, Harvard University, Cambridge, MA, United States, 2Department of Cellular and Molecular Medicine, Center for Epigenomics, University of California, San Diego School of Medicine, La Jolla, CA, United States, 3Current address: Westlake Laboratory of Life Sciences and Biomedicine, School of Life Sciences, Westlake University, Hangzhou, China, 4Department of Neurobiology, Harvard Medical School, Howard Hughes Medical Institute, Boston, MA, United States

11:10
Recognition Of Predator Threat Through The Vomeronasal Organ In Mice
Sachiko Haga-Yamanaka
University of California, Riverside, CA, United States

11:35
Brain-Wide Networks That Control Olfactory Navigation In C. Elegans
Talya S Kramer1,2, Flossie K Wan1, Adam A Atanas1, Sarah M Pugliese1, Jinyue Luo1, Steven W Flavell1
1Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, United States, 2MIT Biology Graduate Program, Massachusetts Institute of Technology, Cambridg, MA, United States

12:00 - 1:00 PMLunch On Own
Lunch on Own

1:00 - 3:00 PMCalusa EFGH
Structural Biology of Chemosensory Receptors

Chair(s): Hiro Matsunami
1:00
Introduction

1:02
Molecular Recognition Of An Aversive Odorant By The Murine Trace Amine-Associated Receptor Taar7F
Christopher Tate1, Anastasiia Gusach1, Yang Lee1, Armin Nikpour Khoshgrudi2, Elizaveta Mukhaleva3, Ning Ma3, Eline Koers2, Qingchao Chen1, Patricia Edwards1, Fanglu Huang4, Jonathan Kim5, Filippo Mancia5, Dmitry Verprintsev2, Nagarajan Vaidehi3, Simone Weyand4
1MRC Laboratory of Molecular Biology, Cambridge, United Kingdom, 2University of Nottingham, Nottingham, United Kingdom, 3Beckman Research Institute of the City of Hope, Duarte, CA, United States, 4University of Cambridge, Cambridge, United Kingdom, 5Columbia University, New York, NY, United States

1:27
Structural And Functional Studies On Bitter Taste Receptors
Weixiu Xu1,2, Tian Hua1,2, Zhijie Liu1,2
1iHuman Institute, ShanghaiTech University, Shanghai, China, 2School of Life Science and Technology, ShanghaiTech University, Shanghai, China

1:52
Making Sense Of Scents: Structural Insights Into Odor Detection
Navid Paknejad, Xiao Fan, Dragana Nesic, Beth Graczyk, Vanessa Ruta
Rockefeller University/HHMI

2:17
Molecular Mechanisms Of Sensory Adaptation
Corey AH Allard, Nicholas W Bellono
Harvard University , Cambridge, MA, United States

2:35
How Do Mammalian Odorant Receptors Recognize Odorants?
Hiro Matsunami
Duke University, Durham, NC, United States

1:00 - 3:00 PMCalusa ABC
Action olfaction across species

Chair(s): Matt Smear
1:00
Introduction
Matt Smear
University of Oregon

1:02
Perceptual And Non-Perceptual Components Of Sniff Responses To Odors
Vivek Sagar1, Guangyu Zhao1, Gregory Lane1, Thorsten Kahnt2, Christina Zelano1
1Northwestern University, Chicago, IL, United States, 2NIDA Intramural Research Program, Baltimore, MD, United States

1:27
Don Tucker Finalist: Respiration Coordinates The Olfactory Cortical Code
Robin M Blazing, Kevin M Franks
Duke University School of Medicine, Durham, NC, United States

1:45
The Impact Of Olfactory Cues On Mouse Social Vocalizations
Joshua P. Neunuebel
University of Delaware, Newark, DE, United States

2:10
Bilateral Sensory Signals For Odor Source Localization In Freely-Moving Mice
Kevin Bolding1, Jiayue Tai2, Dan Leman3, Ian Davison4
1Monell Chemical Senses Center, Philadelphia, PA, United States, 2Tufts University, Department of Biology, Medford, MA, United States, 3Brandeis University, Department of Biology, Waltham, MA, United States, 4Boston University, Department of Biology, Boston, MA, United States

2:35
Genetic Dissection Of Active Antennal Sensing Circuits And Mechanisms In Drosophila
Marie P Suver1, 2, Ashley M Medina2, Katherine I Nagel2
1Vanderbilt University, Nashville, TN, United States, 2NYU Langone Health, New York, NY, United States

3:00 - 3:30 PMCalusa Foyer
Coffee Break

3:30 - 4:30 PMCalusa ABC
The Barry Davis Funding Workshop for New Investigators

This workshop will include an overview of research, training, and funding opportunities for graduate students, postdoctoral fellows, and early stage investigators. The discussion will provide practical information on how grant applications are processed within NIH/NIDCD, including Institute and study section assignments, the peer review process, Advisory Council activities, pay lines, and the roles of program and review staff.


Chair(s): Susan Sullivan, Ph.D
3:30 - 5:00 PMGreat Egret
HISTORY JOURNAL CLUB – 2024: APPETITION

This year’s journal club will highlight the classic work of Anthony Sclafani in uncovering key principles of a phenomenon that he coined “appetition”. In contrast to satiation, where post-ingestive signals suppress gustatory pleasantness (that third piece of cake doesn’t taste nearly as good!), appetition refers to the processes that promote ingestive behaviors. Tony’s work emphasized a paradigm-shifting concept- that there are also post-ingestive reward signals. This has a number of important implications-- not only do such signals amplify hedonic value of tastes but they can also differentially condition liking. The interaction between taste and post-ingestive reward signals has a major impact on driving eating behavior and food choice. During the journal club, we will also discuss recent work that has begun to uncover the peripheral and central mechanistic bases for these phenomena.

Introduction: Dr. Ann-Marie Torregrossa

CLASSIC PAPER

Dr. Anthony Sclafani
• Zukerman S., Ackroff, K. and Sclafani, A Rapid post-oral stimulation of intake and flavor conditioning by glucose and fat in the mouse. Am J Physiol Regul Integr Comp Physiol 301: R1635-R1647, 2011

TO THE PRESENT: Dr. Molly McDougle
• Separate gut-brain circuits for fat and sugar reinforcement combine to promote overeating Molly McDougle 1, Alan de Araujo 2, Arashdeep Singh 3, Mingxin Yang 3, Isadora Braga 4, Vincent Paille 5, Rebeca Mendez-Hernandez 6, Macarena Vergara 2, Lauren N Woodie 7, Abhishek Gour 8, Abhisheak Sharma 8, Nikhil Urs 9, Brandon Warren 10, Guillaume de Lartigue 1Cell Metab 2024 Feb 6;36(2):393-407.

Wrap-up: other relevant data & synthesis (Dr. Lindsey Schier)


4:30 - 4:45 PMCalusa ABC
The BRAIN Initiative® Program: Understanding Circuits Program Funding Opportunities

The National Institute on Deafness and Other Communication Disorders (NIDCD), one of the participating institutes in the NIH BRAIN Initiative, is hosting an informative workshop on the BRAIN initiative program. The workshop will include an overview of various funding opportunities and guidance for prospective and current NIDCD applicants.


Chair(s): Merav Sabri, Ph.D.
4:45 - 5:00 PMCalusa ABC
NIDCD Extramural Clinical Trials

This workshop will provide investigators an overview of how NIDCD approaches extramural clinical trials. The goal of this session is to help investigators determine clinical trials risks, select the most appropriate funding opportunity as well as highlight important points to consider when planning an NIDCD clinical trial. Investigators will also gain an understanding of how NIDCD manages clinical trials.


Chair(s): Trinh Ly, MD
5:00 - 5:45 PMCalusa ABC
AChemS 2024 Codefest Presentations

Participants from the AChemS 2024 Codefest will present their findings from the new Olfaction Challenge dataset.


5:00 - 6:00 PMGreat Egret
Meet the Editors

Chemical Senses is the premier journal focused on the science of smell, taste and chemesthesis in humans and other animals. It is also the official journal of five scientific societies devoted to chemosensory science, including the Association for Chemoreception Sciences. This session will discuss the many advantages of publishing in your society journal, the journal's review and publication processes, and journal policies and new initiatives. After a short presentation by Editor-in-Chief Steven Munger, the session will include a Q&A session with a panel of the journal's executive editors to address questions from the audience and add their own perspectives.


5:00 - 6:00 PMCalusa Foyer
Career/Networking Social

6:00 - 7:00 PMDinner On Own
Dinner On Own

7:00 - 9:00 PMCalusa EFGH
Award Lectures

Chair(s): Alfredo Fontanini
7:00
Achems Young Investigator Awardee

7:30
Award For Research Excellence In The Psychophysics Of Human Taste And Smell

8:00
Ajinomoto Awardee

8:30
Max Mozell Awardee

9:00 - 11:00 PMEstero Ballroom
Poster Session II

P101
Genetic Deletion Of Ace2 In Taste Buds Alters Peripheral Taste Function And Lingual Macrophage Density In Male Mice
Emma Heisey1, Jaeshia Lindsay1, Guangkuo Dong3, William Garcia1, Yang Shi2, Lin Gan1, Lynnette McCluskey1
1Department of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, GA, United States, 2Division of Biostatistics and Data Science, Department of Population Health Sciences, Medical College of Georgia, Augusta University, Augusta, GA, United States, 3Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States

P103
The Relationship Between Chronic High Fat Diet Consumption And Taste Bud Number In Male And Female Rats.
Daniel /M Gaines, Lisa/ A Eckel
Florida State University, Tallahassee, FL, United States

P105
Endogenous Tagging Of The Proton Channel And Sour Receptor Otop1 Reveals Its Apical Localization In Taste Receptor Cells
Joshua P. Kaplan1, Ziyu Liang1, Paul Cohen2, Emily R. Liman1
1University of Southern California, Department of Neurobiology, Los Angeles, CA, United States, 2Rockefeller University, Department of Molecular Metabolism of , New York, NY, United States

P107
Title: Immune Surveillance Pathways In Taste Papillae
Abdul Hamid Siddiqui, Salin Raj Palayyan, Sunil K Sukumaran
University of Nebraska- Lincoln, Lincoln, NE, United States

P109
More Than Fat And Protein: Product Characteristics That Contribute To Reduction Of Capsaicin-Induced Oral Burn
Justin M Gaiser1, 2, John E Hayes1, 2
1Sensory Evaluation Center, The Pennsylvania State University, University Park, PA, United States, 2Department of Food Science, The Pennsylvania State University, University Park, PA, United States

P111
Improved In Silico Models Of The Bitter Taste Receptors Facilitate Drug Discovery Using A Combination Of Traditional High Throughput Screening And Machine Learning Approaches
Muhammad Mirza1, Purshotam Sharma1, Daniel Meister1, Aziz Abu-Saleh1, Michael French2, Richard Ho2, Pat Charmley2, John Trant1
1Trant Lab, University of Windsor, Windsor, Canada, 2Amaro Therapeutics, Inc., New York, NY, United States

P113
Human Parietal Cells In Culture Release Satiating Serotonin In Response To Bitter Peptides Formed During Digestion Of Pea Protein Hydrolysates, And Demonstrate Enhanced Mechanisms Of Gastric Acid Secretion Via Bitter Taste Receptors Tas2R4 And Tas2R43
Katrin Gradl1,3, Veronika Somoza2,3,4
1TUM School of Life Sciences, Technical University of Munich, Freising, Germany, 2Chair of Nutritional Systems Biology, Technical University of Munich, Freising, Germany, 3Leibniz Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany, 4Department of Physiological Chemistry, Faculty of Chemistry, University of Vienna,, Vienna, Austria

P115
Taste Signaling Proteins Play A Protective Role In Response To Pathobiont Microbes In The Colon
Defu Yu1, Hao Lei1, Yan-Bo Xue1, Yi-Hong Li1, Shi-Meng Gong1, Yuan-Yuan Peng1, Kai-Fang Liu1, Damiano Buratto1,2, Yisen Yang1, Sai-Sai Zhang1, Ruhong Zhou1,2, Liquan Huang1
1Zhejiang University, Hangzhou, China, 2Zhejiang University Shanghai Institute for Advanced Study, Shanghai, China

P117
Molecular Basis Of Bitter Taste Receptor Tas2R1 Activated By Anti-Hiv Drugs Lopinavir And Ritonavir
Jiao Wen1, Xinyi Zhou1, Yongcheng Lu1, Shurui Chen1, Keman Xu1, Meng Cui1, 2
1Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, MA, United States, 2Center for Drug Discovery, Boston, MA, United States

P119
Olfactory Stimulation Induces Fragrance-Specific Modulation Of Physiological Biomarkers Associated With Arousal, Vigilance, And Sustained Attention
Robert Assini, Lalit Damodaran, Anshul Jain
International Flavors & Fragrances, Inc., R&D, Union Beach, NJ, United States

P121
Rational Design Of Antagonists For Cigarette Smoke Odors
Timothy S. McClintock1, Evan Meredith1, Abby Frazier1, Samantha L. Schnabel1, Matthew Andres2, Marissa L. Kamarck2,3, Paul M. Wise2,4, Pamela H. Dalton2, Joel D. Mainland2,3
1University of Kentucky, Lexington, KY, United States, 2Monell Chemical Senses Center, Philadelphia, PA, United States, 3University of Pennsylvania, Philadelphia, PA, United States, 4Drexel University, Philadelphia, PA, United States

P123
Effects Of Physical Exercise And Olfactory Training With Pleasant And Unpleasant Odors On Verbal Fluency And Depression
Agnieszka Sabiniewicz1,2, Aleksandra Reichert2, Anna Oleszkiewicz1,2, Antje Haehner1, Thomas Hummel1
1Smell & Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany, 2Institute of Psychology, Department of Historical and Pegagogical Sciences, University of Wroclaw, Wrocław, Poland

P125
Greater Olfactory Awareness Promotes Increased Connectedness To Nature And Wellbeing
Jonas Yde Junge1,2, Chaja Levy3, Connor Lashus3, Gregory Bratman3, Valentina Parma1
1Monell Chemical Senses Center, Philadelphia, PA, United States, 2Aarhus University, Department of Food Science, Aarhus, Denmark, 3University of Washington, Seattle, WA, United States

P127
Don Tucker Finalist: Developmental Changes In Retronasal Smell Perception In Early Childhood
Sarah E. Colbert, Gaby de la Vega, Madison Patel, Joost X. Maier
Wake Forest University School of Medicine, Winston-Salem, NC, United States

P129
Fezf1 Is Required For The Proper Development Of The Terminal Nerve Of Rodents.
Enrico Amato1,2,3, Ed Zandro M Taroc1,2,3, Paolo E Forni1,2,3
1Department of Biological Sciences, University at Albany, State University of New York, Albany, NY, United States, 2The RNA Institute, University at Albany, State University of New York, Albany, NY, United States, 3The Center for Neuroscience Research, University at Albany, State University of New York, Albany, NY, United States

P131
Tracing The Multipotent P63/Keratin5 Basal Progenitor Cells Of The Non-Sensory Epithelium Of The Vomeronasal Organ Of Rodents.
Noah M. LeFever1,2, Raghu Ram Katreddi1,2, Nikki M. Dolphin1,2, Nick A. Mathias1,2, P. E. Forni1,2,3
1Department of Biolological Sciences, University at Albany State University of New York, Albany, NY, United States, 2The RNA Institute, University at Albany State University of New York, Albany, NY, United States, 3The Center for Neuroscience Research, University at Albany State University of New York, Albany, NY, United States

P133
Inhibition Of Fak Promotes Olfactory Neurogenesis And Function Recovery Following Acute Inflammation Through Cntf
Derek Cox, Brian Wang, Joe Oliver, Theo Hagg, Cuihong Jia
East Tennessee State University, Johnson City, TN, United States

P135
Dream Olfactory Mixtures Prediction Challenge
Joe Mainland1, Andreas Keller2, Leslie Vosshall2,3,4, Jake Albrecht5, Pablo Meyer6
1Monell Chemical Senses Center,, philadelphia, PA, United States, 2Laboratory of Neurogenetics and Behavior, NY, NY, United States, 3Howard Hughes Medical Institute, NY, NY, United States, 4 Kavli Neural Systems Institute, NY, NY, United States, 5Sage Bionetoworks, Seatlle, WA, United States, 6IBM Research, NY, NY, United States

P137
Exploring The Impact Of &Ldquo;Kokumi Compounds&Rdquo; On The Psychophysics Of Tastes Perception
Jing Wu, Yao Jiang, Tiffany Hsu, Milan Poland, Leto Solla, Robin Dando, Terry Acree
Cornell University, Ithaca, NY, United States

P139
Autoclaving Polymer-Based Canine Detection Training Aids Prior To Odor Capture Alters Absorptive Properties And Headspace Composition
Samantha Hagerty1, Michelle Aono1, Adam Rivers3, Melissa Singletary1,2
1Department of Anatomy, Physiology, and Pharmacology, Auburn University, Auburn, AL, United States, 2Canine Performance Sciences, Auburn University, Auburn, AL, United States, 3United States Department of Agriculture, Agriculture Research Service, Gainesville, FL, United States

P141
Discrimination Between Food Odours In Pinnipeds: Do They Show Some Preferences ?
Jules Brochon1,2,3, Isabelle Charrier2, Baptiste Mulot3, Gérard Coureaud1
1Centre de Recherche en Neurosciences de Lyon (CRNL), INSERM U1028, CNRS UMR 5292, Université Claude Bernard Lyon 1, Université Jean Monnet, CH Le Vinatier Bâtiment Neurocampus, 69675 Bron, France, 2Université Paris-Saclay, Université Paris-Sud, CNRS, UMR 9197, Institut des Neurosciences Paris-Saclay, 91400 Saclay, France, 3ZooParc de Beauval & Beauval Nature, 41110 Saint-Aignan, France

P143
The Behavioral Sensitivity Of Mice To Acyclic, Monocyclic, And Bicyclic Monoterpenes
Ellie Williams, Austin Pauley, Adam Dewan
Florida State University, Tallahassee, FL, United States

P145
Achems Undergrad Finalist: Olfactory Bulb Local Field Potentials Track Breathing Rhythms At Multiple Timescales 
Sid Rafilson1, Morgan Brown1, Matt Smear1,2
1University of Oregon, Institute of Neuroscience, Eugene, OR, United States, 2University of Oregon, Department of Psychology, Eugene, OR, United States

P147
The Influence Of Respiration And Nasal Airflow On Olfactory And Non-Olfactory Signaling Differs Across Neuronal Populations In The Olfactory Bulb
Keith Perkins, John McGann
Rutgers University, Piscataway, NJ, United States

P149
Cell Type- And Layer-Specific Plasticity Of Olfactory Bulb Interneurons Following Olfactory Sensory Neuron Ablation
Sarah Berg, Tenzin Kunkhyen, Taryn Brechbill, Pranitha Pothuri, Alexander Rangel, Ashna Gupta, Claire Cheetham
Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, United States

P151
The Mouse Olfactory Bulb Is Innervated By A Genetically Heterogeneous Population Of Orexin-Expressing Neurons
Meizhu Qi1,2, Debra A. Fadool1,2,3, Douglas A. Storace1,2,3
1Department of Biological Science, Florida State University, TALLAHASSEE, FL, United States, 2Program in Neuroscience, Florida State University, TALLAHASSEE, FL, United States, 3Institute of Molecular Biophysics, Florida State University, TALLAHASSEE, FL, United States

P153
Sensory-Induced Gamma Oscillations In The Olfactory Bulb Reflect Cognitive Load
Huibo Li1,2, Abigail Stuart1, Jamie Zeng3, Nasya Becton3, Emma Bell3, Leslie M. Kay1,2,3
1Institute for Mind and Biology, The University of Chicago, Chicago, IL, United States, 2Department of Psychology, The University of Chicago, Chicago, IL, United States, 3The College, The University of Chicago, Chicago, IL, United States

P155
Salivary Amylase Regulates Blood Glucose
Kamila D. Nixon1, Emily Demieri1, Kimberly F. James1, Petar Pajic2, Charles Lee3, Omer Gokcumen2, Ann-Marie Torregrossa1,4
1Department of Psychology, University at Buffalo, Buffalo, NY, United States, 2Department of Biological Sciences, University at Buffalo, Buffalo, NY, United States, 3The Jackson Laboratory for Genomic Medicine, Farmington, CT, United States, 4Center for Ingestive Behavior, University at Buffalo, Buffalo, NY, United States

P157
"The Relative Effectiveness Of Intraoral Vs. Intragastric Infusions Of Glucose To Elicit Release Of Insulin And Glucose-Dependent Insulinotropic Polypeptide In The Rat."
Valentina Nisi1, Myrtha Arnold2, Ginger D. Blonde1, Brenna Row1, Graciela Sanchez-Watts3, Alan G. Watts3, Wolfgang Langhans2, Alan C. Spector1
1Department of Psychology and Program in Neuroscience, Florida State University, tallahassee, FL, United States, 2Physiology and Behavior Laboratory, ETH Zurich, Schwerzenbach, Switzerland, 3Department of Biological Sciences, University of Southern California, Los Angeles, CA, United States

P159
Olfactory Nudging Promotes Short-Term Weight Loss
Victoria Esparza1, Angela Pfammatter2, Valentina Parma3, Surabhi Bhutani1
1San Diego State University , San Diego, CA, United States, 2University of Tennessee, Knoxville, TN, United States, 3Monell Chemical Senses Center, Philadelphia, PA, United States

P161
A Graph Neural Network Self Supervised Learning Approach To Generate A Meaningful Chemical Latent Space For Olfactory Tasks
Grant D McConachie, Meg A Younger, Brian DePasquale
Boston University, Boston, MA, United States

P163
Don Tucker Finalist: Human-Associated Odorants Drive Host Invasion In The Human-Infective Nematode Strongyloides Stercoralis
Damia Akimori1,2, Elissa Hallem1
1Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, United States, 2Molecular Biology Interdepartmental PhD Program, University of California, Los Angeles, Los Angeles, CA, United States

P165
Receptors That Detect Human Skin-Derived Carboxylic Acids In Malaria Mosquito
Joshua Raji, Christopher Potter
Johns Hopkins University, Baltimore, MD, United States

P167
Response To Mixtures Of Odorants In A Given Olfactory Receptor/Response Cell Depends On The "Efficacy Ratio" Of The Individual Odorants.
Jonathan Drover1, Hong Elizabeth2, O'Connell Tom2
1Weill Cornell Medical College, New York, NY, United States, 2Caltech, Pasadena, CA, United States

P169
The Role Of Tex15 In Shaping Stochastic Olfactory Receptor Gene Choice
Nusrath Yusuf1, Jerome Kahiapo1, David Brann3, Alina Irvine2, Pavithra Veera1, Irina Ruzina1, Mallika Ravi1, Bob Datta3, Kevin Monahan1
1Rutgers University, New Brunswick, NJ, United States, 2Swarthmore College, Swarthmore, PA, United States, 3Havard Medical School, Boston, MA, United States

P171
Is Mouse Nose A Miniature Version Of A Rat Nose? - A Further Examination Of The Coiled Parallel Olfactory Gas Chromatograph Theory
Zhenxing Wu1, Jianbo Jiang2, Fritz W. Lischka2, Kai Zhao1
1Department of Otolaryngology - Head & Neck Surgery, The Ohio State University, Columbus, OH, United States, 2Monell Chemical Senses Center, Philadelphia, PA, United States



Friday, April 19, 2024


7:30 - 9:00 AMEstero Foyer
Continental Breakfast

8:00 - 10:00 AMEstero Ballroom
Poster Session III

P200
Determinants Of Sweet Taste Liking In Individuals Of African And East Asian Ancestry Groups Living In The United States
Lauren Zami1, Fabien Ca1, Faye Guarneri1, Liz Cortes1, Janel Clovis1, Caren Ghali1,2, May M Cheung1
1City University of New York, Brooklyn College, Brooklyn, NY, United States, 2City University of New York, Macaulay Honors College, New York, NY, United States

P202
The Scent Of Organo Leaves Regulates Sodium Chloride Consumption In Mice.
Kazumi Osada1, Motoko Ohata1, Nana Aoyagi1, Akira Hosono1, Issei Yokoyama1, michio komai2
1Nihon University, Fujisawa, Japan, 2Tohoku University, Sendai, Japan

P204
Comparing Sensory And Emotional Responses To Chemosensory Stimuli Between Autistic And Neurotypical Children
Asmita Singh1, Khoa Luu2, Se-Woong Park3, Leslie Neely4, Han-Seok Seo1
1Department of Food Science, University of Arkansas, Fayetteville, AR, United States, 2Department of Electrical Engineering and Computer Science, Fayetteville, AR, United States, 3Department of Kinesiology, University of Texas at San Antonio, San Antonio, TX, United States, 4Department of Educational Psychology, University of Texas at San Antonio, San Antonio, TX, United States

P206
The Geometry And Role Of Sequential Activity In Olfactory Processing And Perceptual Generalization
Jonathan V Gill1, Mursel Karadas1, Shy Shoham1,3,5, Dmitry Rinberg1,2,4
1NYU Langone Health, Neuroscience Institute, New York, NY, United States, 2New York University, Center for Neural Science, New York, NY, United States, 3NYU Langone Health, Tech4Health Institute, New York, NY, United States, 4New York University, Dept. of Physics, New York, NY, United States, 5NYU Langone Health, Dept. of Ophthalmology, New York, NY, United States

P208
Frequency-Dependent Phase Locking Of Tubular Striatum Neurons To The Respiratory Cycle In Behaving Mice
Zihao Zhang1, Marie Gadziola2, Daniel Wesson1
1University of Florida, Gainesville, FL, United States, 2University of Toronto Scarborough, Toronto, Canada

P210
Understanding The Odorant Receptor-Based Configurational Coding Of Walnut Odor
Franziska Haag, Dietmar Krautwurst
Leibniz-Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany

P212
Evolution And Functional Characterization Of Olfactory Receptors In Birds
Robert Driver1, Christopher Balakrishnan2, Hiroaki Matsunami1,3,4,5
1Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, United States, 2Department of Biology, East Carolina University, Greenville, NC, United States, 3Duke Cancer Institute, Duke University, Durham, NC, United States, 4Duke Institute for Brain Science, Duke University, Durham, NC, United States, 5 Duke Initiative for Science & Society, Duke University, Durham, NC, United States

P214
Don Tucker Finalist: Investigating The Mechanisms Of Enantiomer Discrimination By An Odorant Receptor
Ichie Ojiro1,2, Keisuke Ito1, Claire A. de March3, Hiroaki Matsunami2
1Department of Food and Nutritional Sciences, Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, Shizuoka, Japan, 2Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, United States, 3Institut de Chimie des Substances Naturelles, UPR2301 CNRS, Université Paris-Saclay, Gif- sur- Yvette, France

P216
Conspecific Odor Representation In Piriform Cortex
Ryan C. Scauzillo, Max L. Fletcher
University of Tennessee Health Science Center, Memphis, TN, United States

P218
The Role Of The Higher-Order Brain Regions In Olfactory Identification
Rommy Elyan1, Qing Yang1,2, Paul Eslinger1,3, Arthur Berg4, Sangam Kanekar1, Will Jens3, Deepak Kalra3, Biyar Ahmed1, Senal Peiris1, Ran Pang1, Prasanna Karunanayaka1
1Department of Radiology, Penn State University College of Medicine, Hummelstown, PA, United States, 2Department of Neurosurgery, Penn State University College of Medicine, Hershey, PA, United States, 3Department of Neurology, Penn State University College of Medicine, Hershey, PA, United States, 4Department of Public Health Sciences, Penn State University College of Medicine, Hershey, PA, United States

P220
The Role Of Trigeminal Activation In Perceived Odor Intensity
Aiden Streleckis, Robert Pellegrino, Matthew Andres, Johannes Reisert, Joel Mainland, Federica Genovese
Monell Chemical Senses Center, Philadelphia, PA, United States

P222
The Social Vocalizations And Behavior Of Olfaction-Impaired Mice
Kaihang C Chen, Zoe L Shteyn, Joshua P Neunuebel
University of Delaware, Newark, DE, United States

P224
Single Cell Transcriptomics Of Vomeronasal Neuroepithelium Reveals A Differential Endoplasmic Reticulum Environment Amongst Neuronal Subtypes
Devakinandan G V S, Adish Dani
Tata Institute of Fundamental Research, Hyderabad, India

P226
Impaired Iron Gluconate Identification In Sars-Cov-2 Igg+ Subjects And Associated Lower Transcript Levels Of The Human Foliate Papillae Tongue Transcriptome
Barbara Danzer1,2, Mateo Jukic3, Andreas Dunkel2, Gaby Andersen2, Barbara Lieder4,5, Erika Schaudy6, Sarah Stadlmayr4, Jory Lietard6, Timm Michel1,2, Dietmar Krautwurst2, Bernhard Haller7, Percy Knolle8, Mark Somoza2,6,9, Paul Lingor3,10,11, Veronika Somoza2,4,12
1Technical University of Munich, School of Life Science, Freising, Germany, 2Leibniz Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany, 3Department of Neurology, Klinikum rechts der Isar, Technical University of Munich, School of Medicine and Health, Munich, Germany, 4Department of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria, 5Current address: Institute of Clinical Nutrition, University of Hohenheim, Stuttgart, Germany, 6Department of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria, 7Institute of AI and Informatics in Medicine, School of Medicine and Health, Technical University of Munich, Munich, Germany, 8Institute of Molecular Immunology, School of Medicine and Health, Technical University of Munich, Munich, Germany, 9Chair of Food Chemistry and Molecular Sensory Science, School of Life Sciences, Technical University of Munich, Freising, Germany, 10German Center for Neurodegenerative Diseases (DZNE), Munich, Germany, 11Munich Cluster for Systems Neurology (SyNergy), Munich, Germany, 12Chair of Nutritional Systems Biology, School of Life Sciences, Technical University of Munich, Freising, Germany

P228
Taste And Smell Disorders In The United States: Risk Factors And Healthy People 2030
Howard J. Hoffman1, Chuan-Ming Li1, Shristi Rawal2, Valerie B. Duffy3
1Epidemiology, Statistics, and Population Sciences, NIDCD, NIH, Bethesda, MD, United States, 2Department of Clinical and Preventive Nutrition Sciences, Rutgers University, Newark, NJ, United States, 3Department of Allied Health Sciences, University of Connecticut, Storrs, CT, United States

P230
Identification And Confirmation Of Neurocircuit For Petrification And Micturition
Pengjie Wen1, Zhenxiang Shi2, Yuxiang Qiu2, Fuqiang Xu1,2
1Shenzhen Institute of Advanced Technology, CAS, Shenzhen, , 2Wuhan Institute of Physics and Mathematics, CAS, Wuhan,

P232
Central Terminals Of Penk+ (T3) Gustatory Neurons Show A Regionally Restricted Distribution
Kathleen Depina1, Gennady Dvoryanchikov1, Judith Rosales Rivas1, Andoni Asencor 1, Nirupa Chaudhari1,2
1Department of Physiology & Biophysics, University of Miami Miller School of Medicine, Miami, FL, United States, 2Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL, United States

P234
Exploring The Underlying Circuit Mediating Grp-Grpr Signaling Between Gustatory Cortex And Basolateral Amygdala
Aylar Berenji Kalkhoran, Alfredo Fontanini, Arianna Maffei
Dept. Neurobiology and Behavior, SUNY Stony Brook, Stony Brook, NY, United States

P236
Differential Effects Of Amiloride And Benzamil On Salt Taste Physiology And Behavior: The Case For Phasic Responses In The Generation Of Na+ Appetite
Sarah A Randall, Kira C Grapentine, Yashoda Das K, Joseph M Breza
Eastern Michigan University, Ypsilanti, MI, United States

P238
Parabrachial Cgrp Neurons Affect Taste-Guided Behaviors
Christian H Lemon, Jinrong Li, Kyle T Zumpano, Catori J Roberts, Traci L Redwine, Damilola V Adesina
University of Oklahoma, Norman, OK, United States

P240
Sniffing Behaviors Of Freely Behaving Mice
Jonah E Pearl, Caleb Weinreb, Sandeep R Datta
Dept. of Neurobiology, Harvard Medical School, Boston, MA, United States

P242
Modulation Of Pharmaceutical Taste Aversiveness In Drosophila Melanogaster
Paul Breslin1,2, Natasha Rivers2, Carter Green3
1Rutgers University, New Brunswick, NJ, United States, 2Monell Chemical Senses Center, Philadelphia, PA, United States, 3Takasago International Corporation (U.S.A.), Rockleigh, NJ, United States

P244
Mice Learn To Identify And Discriminate Sugar Solutions Based On Olfactory Cues
John I Glendinning1, Alix Archambeau1, Gabriel Griffith1, Kayla Koffler1, Gabriella Ortiz1, Cathernine Sollitto1, Harini Srinivasan1
1Barnard College, Columbia University, New York, NY, United States, 2Barnard College, Columbia University, New York, NY, United States, 3Barnard College, Columbia University, New York, NY, United States, 4Barnard College, Columbia University, New York, NY, United States, 5Barnard College, Columbia University, New York, NY, United States, 6Barnard College, Columbia University, New York, NY, United States, 7Barnard College, Columbia University, New York, NY, United States

P246
Palatability Modulation Of Amino Acid-Based Oral Rehydration Therapy In Children
Caroline Payton Harmon1, Jennifer M. Manuola1, Amani Hill1, Paul A.S. Breslin1,2
1Rutgers University, New Brunswick, NJ, United States, 2Monell Chemical Senses Center, Philadelphia, PA, United States

P248
Aging Decreases Behavioral Preferences For Salts, But Not For Sucrose, And Alters The Ultrastructural Morphology Of Fungiform Taste Pores In Mice
Kolbe M Sussman, Joseph M Breza
Eastern Michigan University, Ypsilanti, MI, United States

P250
Don Tucker Finalist: Dietary Habits Can Affect Fat Intake Independent Of Obesity
Nicholas Amado1, Judith Storch1, Paul Breslin1,2
1Rutgers University, New Brunswick, NJ, United States, 2Monell Chemical Senses Center, Philadelphia, PA, United States

P252
Emergence Of Adaptive Taste Choices In A Closed-Loop Task
Kennedy H Watson, Joost X Maier
Wake Forest University School of Medicine , Winston Salem , NC, United States

P254
The Role Of Saliva In Astringency Perception Of Cocoa Polyphenols
Cynthia Loi1,2, Helene Hopfer1,2, John Hayes1,2
1Sensory Evaluation Center, The Pennsylvania State University, University Park, PA, United States, 2Department of Food Science, The Pennsylvania State University, University Park, PA, United States

P256
Assessing Recruitment Strategies And Challenges In Studying Racial And Ethnic Variations In Bitter Taste Perception
Patrice A Hubert1, Ha Nguyen1, Amy Huang1, Paule V Joseph2, Caliu Lin1, May Cheung3, Danielle R Reed1
1Monell Chemical Senses Center, Philadelphia, PA, United States, 2National Institute of Health, Bethseda, MD, United States, 3Brooklyn College City University of New York, Brooklyn, NY, United States

P258
Adiponectin Signaling Modulates Fat Taste Responsiveness And Sensitivity In Mice
Fangjun Lin1, Timothy A. Gilbertson2
1Burnett School of Biomedical Sciences , University of Ceentral Florida, Orlando, FL, United States, 2Department of Internal Medicine, University of Central Florida, Orlando, FL, United States

P260
Selective Increases In Taste Sensitivity To Glucose As A Function Of Hunger Status
Laura E Martin1,2, Juyun Lim1
1Oregon State University, Corvallis, OR, United States, 2Coca-Cola , Atlanta, GA, United States

P262
Otop1 Mediates Chorda Tympani And Behavioral Responses To Ammonium Chloride (Nh4Cl)
Courtney E Wilson1, Ziyu Liang2, Bouchuan Teng3, Emily R Liman2, Sue C Kinnamon1
1University of Colorado School of Medicine, Aurora, CO, United States, 2University of Southern California, Los Angeles, CA, United States, 3Caltech, Pasadena, CA, United States

P264
Mechanism Of Long Term-Lasting Virus-Induced Olfactory Loss
Akihito Kuboki, Jidong Tan, Katelyn Tu, Cailu Lin, Peihua Jiang, Johannes Reisert, Hong Wang
Monell Chemical Senses Center, Philadelphia, PA, United States

P266
Olfaction Evaluation In Dogs With Sudden Acquired Retinal Degeneration Syndrome (Sards)
Kenneth Abrams1, Daniel Ward2, Agnieszka Sabiniewicz3,4, Thomas Hummel3
1Veterinary Ophthalmology Services, North Kingstown, RI, United States, 2University of Tennessee- College of Veterinary Medicine, Knoxville, TN, United States, 3University of Dresden-Smell and Taste Clinic, Dresden, Germany, 4University of Wroclaw- Institutute of Psychology, Wroclaw, Poland

P268
Study Of Chemosensory Enhancement Through Neuromodulation Training (Scent): Design And Methodology Of A Randomized Clinical Trial For Covid-Related Persistent Smell Loss
Bernadette M. Cortese1, Mary Clare Koebel1, Nicole Cash1, Aicko Y. Schumann1,2, Lisa M. McTeague1,3, Thomas W. Uhde1, Rodney J. Schlosser4, Bashar W. Badran1
1Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, United States, 2Department of Mathematics, College of Charleston, Charleston, SC, United States, 3Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC, United States, 4Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, United States

P270
Investigating The Behavioral Effects Of Anosmia And Repetitive Mild Traumatic Brain Injury In A Murine Model
Anthony B. Crum1, Jinxin Wang1, Julian P. Meeks1,2
1Department of Neuroscience, University of Rochester, Rochester, NY, United States, 2Department of Pediatrics, University of Rochester, Rochester, NY, United States

P272
Effects Of Congenital Blindness On The Development And Plasticity Of The Olfactory System : Input From Odor-Evoked Sniffing And Optical Imaging Recordings
Nouhaila Bouguiyoud1, Syrina Al Aïn1, Johannes Frasnelli1, Belkacem Messaoudi2, Samuel Garcia22, Anne-Marie Mouly2, Philippe Litaudon2, Emmanuelle Courtiol2
1Université du Québec à Trois-Rivières, Anatomy, Trois-Rivières, QC, Canada, 2Université Claude Bernard Lyon 1, CNRS, INSERM, Centre de Recherche en Neurosciences de Lyon CRNL, U1028 UMR5292, CMO, Lyon, France

P274
Digital Accessible Remote Olfactory Mediated Health Assessments For Preclinical Ad
Andreas Runde1, Colin Magdamo1, Alysa Alejandro Soto1, Benoit Jobin1,2, Alefiya Albers1, Mark Albers1
1Massachusetts General Hospital, Boston, MA, United States, 2Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada

P276
G Protein Coupled Receptors In Sea Lamprey Pharyngeal Tissue Containing Taste Buds
Zeenat Aurangzeb1, Sirinart Ananvoranich1, Gianfranco Grande1, Gheylen Daghfous2, Rejean Dubuc2, Barbara Zielinski1
1University of Windsor, Windsor, ON, Canada, 2Universite de Quebec a Montreal, Montreal, QC, Canada

9:00 - 10:00 AMEstero Foyer
Coffee Break

10:00 - 12:00 PMCalusa EFGH
Exploring Cellular and Molecular Dynamics in the Developing Olfactory System

Chair(s): Paolo Forni
10:00
Exploring Cellular And Molecular Dynamics In The Developing Olfactory System
Paolo Forni1, Ron Yu2
1University at Albany, SUNY, 2Stowers Institute for Medical Research

10:02
Investigating The Molecular Mechanisms Governing Axonal Projections Of Vomeronasal Sensory Neurons
Thelma T Chiremba1, Limei Ma1, Max Hill Jr.1, Hannah Wilson1, Cathy McKinney1, C. Ron Yu1,2
1Stowers Institute for Medical Research, Kansas City, MO, United States, 2University of Kansas Medical Center, Kansas City, KS, United States

10:22
Elucidation Of Mouse Olfactory Glomerular Network
Pavan Rao1, I-Hao Wang1, Hao-Ching Jiang1, Sung Jin Park1, Zhiping Weng1, Fei Chen2, Evan Z. Macosko2, Paul L. Greer1
1University of Massachusetts Chan Medical School, Worcester, MA, United States, 2Broad Institute of Harvard and MIT, Cambridge, MA, United States

10:42
Mechanisms Controlling Specification Of Olfactory Receptor Neuron Subtypes
Kevin Monahan
Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ, United States

11:07
Glomerular Map Formation In The Control Of Social Behaviors
Sydney Fearnley1,2, Neelima Vaddadi1,3, Emilie Dumontier1, Jean-Francois Cloutier1,2,3
1Montreal Neurological Institute and Hospital, Montreal, QC, Canada, 2Anatomy and Cell Biology, McGill University, Montreal, QC, Canada, 3Neurology and Neurosurgery, McGill University, Montreal, QC, Canada

11:32
Terminal Nerve Cells In Rodents As A Bridge Between Olfactory Development And Fertility
Rico Amato, Ed Zandro M Taroc, Paolo E. Forni
Biology Department -The RNA Institute, University at Albany

10:00 - 12:00 PMCalusa ABC
Coding Principles in the Olfactory and Gustatory Cortex

Chair(s): Kevin Franks
10:00
Introduction

10:02
Synaptic Plasticity And Ensemble Representation In Piriform Cortex
Anne-Marie M. Oswald
Neurobiology, Neuroscience Institute, University of Chicago, Chicago, IL, United States

10:25
Learning Embeds Mixed-Selectivity And Associative Encoding In Piriform Cortex
Antonia Marin-Burgin
IBioBA-CONICET-Max Planck partner Institute, Buenos Aires, Argentina

10:50
Exploring Drift In Gustatory Cortex Taste Identity And Valence Representations
Max Fletcher, Martin A Raymond, John D Boughter
University of Tennessee Health Science Center

11:13
Coding In The Gustatory Cortex: Tasting The Past, The Present And The Future
Alfredo Fontanini
Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, NY, United States

11:36
Smell The Lizard: Ancestral Molecular Signatures Of Olfactory Cortex Neurons
Sara Zeppilli1, Alonso Ortega Gurrola2, Pinar Demetci3, David H. Brann4, Noga Zilkha5, Tali Kimchi5, Sandeep R. Datta4, Ritambhara Singh3, Maria A. Tosches2, Anton Crombach6, Alexander Fleischmann1
1Department of Neuroscience and Carney Institute for Brain Science, Brown University, Providence, RI, United States, 2Department of Biological Sciences, Columbia University, New York, NY, United States, 3Department of Computer Science, Center for Computational Molecular Biology, Brown University, Providence, RI, United States, 4Department of Neurobiology, Harvard Medical School, Boston, MA, United States, 5Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel, 6Inria Centre de Lyon, Villeurbanne, France

12:00 - 1:00 PMCalusa EFGH
Business Meeting

1:00 - 4:30 PMLunch On Own
Free Time

4:30 - 6:00 PMCalusa ABC
The Great Debate: The role of artificial intelligence in olfaction

Recent advances in statistical learning, machine intelligence, chemoinformatics and psychophysics appear to be bringing us closer to a holy grail of chemical biology: to be able to predict what a molecule will smell like based upon its structure alone. But, given the limits of the technologies and data, how close are we to actually reaching this elusive goal? Are these new computational approaches the key to new insights into the biology of smell, or a shiny distraction from the hard experiments necessary to understand how the brain transforms chemistry into perception? What are the right and wrong questions to ask using these methods? And given the deep role played by personal experience in smell, will it ever be possible to make accurate predictions in individuals? Here we assemble a diverse panel of experts to offer their differing perspectives on the promise and perils of AI in the study of smell. Join us as these experts engage in a vigorous open debate to render clear where these approaches stand now, and what progress we can reasonably expect in the future.

Participants:
Bob Datta (Harvard University)
Alex Wiltschko (Osmo)
Noam Sobel (Weitzmann Institute)
Stuart Firestein (Columbia University)
Ann-Sophie Barwich (Indiana University)
Pablo Meyer (IBM)
Barry Smith (University of London)
Joel Mainland (Monell Chemical Senses Center)



Chair(s): Bob Datta
4:30 - 6:00 PMGreat Egret
Demonstrations of test procedures for evaluating human smell and taste function

This workshop will provide participants with first-hand experience in employing a wide range of procedures for assessing human smell and taste function. A brief discussion of the strengths and limitations of each approach to testing will be provided.


Chair(s): Thomas Hummel and Richard Doty
6:00 - 7:00 PMDinner On Own
Dinner on Own

7:00 - 9:00 PMCalusa EFGH
Polak Awards Lectures

The Polak Foundation Awards are in honor of the Elsje Werner-Polak Memorial Fund in memory of our niece gassed by the Nazis in 1944 at age 7: Ghislaine Polak and the late Ernest Polak.


7:00
The Role Of Trigeminal Activation In Perceived Odor Intensity
Aiden Streleckis, Robert Pellegrino, Matthew Andres, Johannes Reisert, Joel Mainland, Federica Genovese
Monell Chemical Senses Center, Philadelphia, PA, United States

7:20
A Glomerular Hierarchy For Olfactory Discriminations
Walter G. Bast1, Cina Aghamohammadi1,2, Priyanka Gupta1, Tatiana Engel1,2, Florin Albeanu1
1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, United States, 2Princeton University, Princeton, NJ, United States

7:40
Utilizing Olfactory Receptor Defined Glomeruli To Understand The Transformation Of Odor Representations In The Mammalian Olfactory Bulb
Madison A. Herrboldt1, Mona A. Marie2, Hiroaki Matsunami2,3, Matt Wachowiak1
1Department of Neurobiology, University of Utah School of Medicine, Salt Lake City, UT, United States, 2Molecular Genetics and Microbiology Department, Duke University School of Medicine, Durham, NC, United States, 3Neurobiology Department, Duke University School of Medicine, Durham, NC, United States

8:00
Basolateral Amygdala And Gustatory Cortex Interact Bidirectionally During Taste Processing In Rodents
Abuzar Mahmood, Jessica Steindler, Donald Katz
Brandeis University, Waltham, MA, United States

8:20
Activation Mechanisms And Competitive Antagonism In Class I Odorant Receptors
Mona A. Marie1, Hiroaki Matsunami1,2,3,4,5
1Molecular Genetics and Microbiology Department, Duke School of Medicine, Durham, NC, United States, 2Neurobiology Department, Duke Schoole of Medicine, Durham, NC, United States, 3Duke Institute for Brain Sciences, Durham, NC, United States, 4Duke Cancer Institute, Durham, NC, United States, 5Duke Initiative for Science & Society, Durham, NC, United States

8:40
An Essential Role For Depolarization Block In Odor Discrimination
David Tadres1,2,*, Philip Wong1,3,*, Naomi Khosalim1, Mariana Lopez4, Matthieu Louis1
1University of California, Santa Barbara, Santa Barbara, CA, United States, 2current address: Stanford University, Palo Alto, CA, United States, 3current address: University of California, Los Angeles, Los Angeles, CA, United States, 4Centre for Genomic Regulation, Barcelona, Spain

9:00 - 11:00 PMEstero Ballroom
Poster Session IV

P201
The Effect Of Furaneol Through Olfactory Stimulation On Spontaneous Locomotor Activity
Motoko Ohata, Momoka Kinowaki, Issei Yokoyama, Masato Tsuda, Akira Hosono, Kazumi Osada
Nihon University, Fujisawa, Japan

P203
Lack Of Salivary Α-Amylase Results In Increased Taste Responding To Medium But Not Long-Chain Maltodextrin
Verenice Ascencio Gutierrez1, Rachel D. Fan1, Kamila D. Nixon1, Emily Demieri1, Kimberly F. James1, Petar Pajic2, Charles Lee3, Omer Gokcumen2, Ann-Marie Torregrossa1,4
1Department of Psychology, University at Buffalo, Buffalo, NY, United States, 2Department of Biological Sciences, University at Buffalo, Buffalo, NY, United States, 3The Jackson Laboratory for Genomic Medicine, Farmington, CT, United States, 4Center for Ingestive Behavior Research, University at Buffalo, Buffalo, NY, United States

P205
Glomerular Sequence Represents Odor Quality In The Mouse Olfactory Bulb
Joshua S Harvey1, Khristina Samoilova2, Hiro Nakayama1, Farhad Pashakhanloo2, Alexei Koulakov2, Dmitry Rinberg1
1Neuroscience Institute, New York University Langone Health, New York, NY, United States, 2Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, United States

P207
Human Piriform Cortical Representations Of Perceived Odor Intensity
Andrew Sheriff1, Guangyu Zhou1, Robert Pellegrino3, Matthew Andres3, Julia Jamka1, Mahmoud Omidbeigi1, Joshua M. Rosenow2, Stephan Schuele1, Chima Oluigbo5, Mohamad Koubeissi6, Gregory Lane1, Joel Mainland3,4, Christina Zelano1
1Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States, 2Department of Neurosurgery, Northwestern University Feinberg School of Medicine, Chicago, IL, United States, 3Monell Chemical Senses Center, Philadelphia, PA, United States, 4Department of Neuroscience, University of Pennsylvania, Philadelphia, PA, United States, 5Division of Neurosurgery, Children's National Medical Center, Washington, DC, United States, 6Department of Neurology, George Washington University, Washington, DC, United States

P209
Chemosensory Encoding In Tangential Inputs To The Drosophila Navigation Center
Kavin M. Nunez, Jacob D. Freed, Katherine Nagel
NYU School of Medicine Neuroscience Institute, New York, NY, United States

P211
Engineering Insect Odorant Receptors As A Detection Mechanism For Disease Associated Volatiles
Rhodry J. Brown1, Gyu Rie Lee2, Hiroaki Matsunami1
1Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, United States, 2Department of Biochemistry, University of Washington, Seattle, WA, United States

P213
Chemosensory Responses To Carbon Dioxide Shape Parasite-Host Interactions In A Skin-Penetrating Human-Infective Nematode.
Navonil Banerjee, Spencer S. Gang, Michelle L. Castelletto, Felicitas Ruiz, Elissa A. Hallem
University of California Los Angeles, Los Angeles, CA, United States

P215
The Role Of Surface Adhesion Molecules In Cellular Connections
Nikki M Dolphin1,2, P.E. Forni1,2,3
1Department of Biological sciences, University at Albany, State University of New York, Albany, NY, United States, 2RNA institute, University at Albany, State University of New York, Albany, NY, United States, 3The Center for Neuroscience Research, University at Albany, State University of New York, Albany, NY, United States

P217
Leveraging Fluid Dynamic Cues For Olfactory Navigation In Turbulent Environments
Elle A. Stark, Aaron C. True, John P. Crimaldi
University of Colorado, Boulder, CO, United States

P219
Tauro-Deoxycholic Acid Modulates Chemosensory Behavior Via The Accessory Olfactory System In Mice
Varun Haran1, Julian P. Meeks1
1Department of Neuroscience, University of Rochester Medical School, Rochester, NY, United States, 2Department of Neuroscience, University of Rochester Medical School, Rochester, NY, United States

P221
The Effect Of Social Experience On Gene Regulation, Neural Activity And Behavior In Drosophila Melanogaster
Chengcheng Du1, Jesus Sotelo Fonseca1, Shania Appadoo1, Luis Garcia1, Morayo Abbey-Bada1, Yuta Mabuchi2, Nilay Yapici2, Corbin D. Jones3, Pelin Volkan1
1Duke University, Durham, NC, United States, 2Cornell University, Ithaca, NY, United States, 3UNC-Chapel Hill, Durham, NC, United States

P223
Transgenic Tools For Investigating Bile Acid Detection And Information Processing In The Mouse Accessory Olfactory System.
Michael A. Mastrangelo1, Varun Haran1, Jie Cao2, Julian P. Meeks1,3
1Department of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States, 2Department of Neuroscience, UT Southwestern Medical Center, Dallas, TX, United States, 3Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States

P225
Homoeriodictyol Counteracts The Bitterness Response Elicited By Pt-Based Chemotherapeutics In A Cellular Model System And Reduces Bitter Phantogeusia In Cancer Patients
Sofie Zehentner1,2, Agnes Mistlberger-Reiner1, Elisabeth Wachter3, Katja Bacovsky1, Michelle Friedrich3, Philip Pirkwieser4, Noreen Orth4, Valerie Boger4, Kristin Kahlenberg4, Johanna Kreißl4, Petra Rust3, Sophie Pils5, Christoph Grimm5, Jakob Ley6, Veronika Somoza1,4,7
1Institute of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria, 2Vienna Doctoral School in Chemistry (DoSChem), University of Vienna, Vienna, Austria, 3Department of Nutritional Sciences, University of Vienna, Vienna, Austria, 4Leibniz Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany, 5Department of General Gynecology and Gynecologic Oncology, Comprehensive Cancer Center Vienna, Gynecologic Cancer Unit, Medical University of Vienna, Vienna, Austria, 6Symrise AG, Research & Technology Flavors Division, Holzminden, Germany, 7Chair of Nutritional Systems Biology, School of Life Science, Technical University of Munich, Freising, Germany

P227
Neurocircuit Identification And Functional Revelation Of Sniffing
Yue Liu1 , Li Wang1, Qing Liu2, Fuqiang Xu1,2
1Wuhan Insttute of Physics and Mathematics, CAS, Wuhan, , 2Shenzhen Institute of Advanced Technology, CAS, Shenzhen,

P229
Gustatory Processing Within And Beyond The Subesophageal Zone In Drosophila
Leah Pappalardo1,2, Yu-Shan Hung1, Mark Stopfer1
1National Institutes of Health - National Institute of Child and Human Development, Bethesda, MD, United States, 2Johns Hopkins University, Baltimore, MD, United States

P231
Elicitation Of Fos Immunoreactivity And Orofacial Behaviors By Intraoral Infusion Of Sodium Carbonate In Rats
Steven J. St. John1, Camille T. King2, Michael S. King3
1Department of Psychology, Rollins College, Winter Park, FL, United States, 2Department of Psychology, Stetson University, DeLand, FL, United States, 3Department of Biology, Stetson University, DeLand, FL, United States

P233
Cortical And Subcortical Connectivity Changes With Taste Neophobia And Attenuation
Mia B. Fox, Martin A. Raymond, John D. Boughter, Max L. Fletcher
Department of Anatomy and Neurobiology, University of Tennessee Health Science Center , Memphis , TN, United States

P235
Trigeminal Co-Stimulation Alters The Eeg Signature Of Olfactory Stimuli
Matin Asghar Pour1, Olivier Fortier-Lebel1, Émilie Hudon1, Sarah Brosse1, Frank Cloutier1, Johannes Frasnelli1,2
1Department of Anatomy, UQTR, Trois-Rivieres, QC, Canada, 2Research Center, Sacré-Coeur Hospital, Montréal, QC, Canada

P237
Neural Circuitry Underlying Negative Valuation Of Sweetness In Drosophila
Dorsa Motevalli1, Sydney Fogleman1, Robert Alfredson1, Ulrich Stern1, Will Silander2, Kaiyu Wang4, Barry Dickson3, Toshihide Hige2, Rebecca Chung-Hui Yang1
1Duke University , Durham, NC, United States, 2University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, 3Queensland Brain Institute, Brisbane, Australia, 4Shanghai Center for Brain Science and Brain-Inspired Intelligence Technology, Shanghai , China

P239
Multimodal Integration Of Olfactory And Gustatory Stimuli In Locust Superior Lateral Protocerebrum And Accessory Calyx Neurons
Brian Kim1,2, Mark Stopfer1
1NIH-NICHD, 2Brown University

P241
A Split-Sample Approach To Examining Sweet Preferences And Alcoholic Beverages
Sara Spinelli1, Caitlin M. Cunningham3, John Prescott1,2, Erminio Monteleone1, Caterina Dinnella1, Theresa White3
1Università degli Studi di Firenze, Florence, Italy, 2TasteMatters Research and Consulting, Sydney, Australia, 3Le Moyne College, Syracuse, NY, United States

P243
Encoding Of Odours With Taste Qualities In The Human Primary Gustatory Cortex
Putu A. Khorisantono1, Maria G. Veldhuizen2, Janina Seubert1
1Division of Psychology, Department fo Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden, 2Department of Psychology, Faculty of Science and Letters, Mersin University, Mersin, Turkey

P245
Discovery Of Bb99: A Potent T2R54 (Tas2R39) Antagonist That Blocks The Bitterness Of Select Active Pharmaceutical Ingredients (Apis)
Joseph R. Fotsing1, Guy Servant1, Qing Chen1, Chad Priest1, Melissa S. Wong1, Antoniette Java1, Yi Ren1, Tanya Ditschun1, Lan Zhang1, Mark Williams1, Michael Saganich1, Hanghui Liu1, Vincent Darmohusodo1, Srini Subramanian2
1dsm-firmenich, San Diego, CA, United States, 2dsm-firmenich, Princeton, NJ, United States

P247
The Power Of Senses - Savoury Taste Phenotypes Modulate Food Acceptance, Consumption And Body Mass Index: Insights From A Large Population Sample
Camilla Cattaneo1, Sara Spinelli2, Caterina Dinnella2, Cristina Proserpio1, Erminio Monteleone2, Ella Pagliarini1, Monica Laureati1
1Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy, 2Department of Agriculture, Food, Environment and Forestry (DAGRI), Florence, Italy

P249
Sourness Of Citric Acid And Citrate Salts In Humans
Astrid E. D'Andrea1,2, John E. Hayes1,2, Helene Hopfer1,2
1Sensory Evaluation Center, The Pennsylvania State University, University Park, PA, United States, 2Department of Food Science, The Pennsylvania State University, University Park, PA, United States

P251
How Bitter Is It? Odor-Induced Bitter Taste Modulation Of Bitter Ligands
Leah Hall 1, Stephanie Okoye 2, Jessica Nicanor-Carreon2, Masha Y. Niv3, M. Yanina Pepino 1,2,4
1Food Science and Human Nutrition, University of Illinois Urbana-Champaign, Urbana , IL, United States, 2Divison of Nutritional Sciences, University of Illinois Urbana-Champaign, Urbana, IL, United States, 3The Institute of Biochemistry, Food and Nutrition, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University, Jerusalem, Israel, 4Carle Illinois College of Medicine, Urbana, IL, United States

P253
The Bitter Taste Of Medicines And Their Modifiers In People Of Diverse Ancestries
Ha Nguyen1, Cailu Lin1, Katherine Bell1, Amy Huang1, Mackenzie Hannum1, Vicente Ramirez1, Carol Christensen1, Nancy E. Rawson1, Lauren Colquitt1, Paul Domanico2, Ivona Sasimovich1, Riley Herriman1, Paule Joseph3, Oghogho Braimah4, Danielle R. Reed1
1Monell Chemical Senses Center, Philadelphia, PA, United States, 2Clinton Health Access Initiative, New York, NY, United States, 3National Institute of Alcohol Abuse and Alcoholism & National Institute of Nursing Research, Bethesda , MD, United States, 4Countess of Chester Hospital, Chester, United Kingdom

P255
Test-Retest Reliability Of Unipolar And Bipolar Electrogustometric Thresholds And Their Association With Waterless Empirical Taste Test (Wett&Reg;) Scores.
Toshi Matsuda1, Robert Brown1, Kasso Peaks1, Richard Doty2
1Sensonics International, Haddon Heights, NJ, United States, 2University of Pennsylvania, Philadelphia, PA, United States

P257
Unique Roles Of Type Ii & Type Iii Taste Cells In Fatty Acid Signaling
Emeline Masterson1,2, Fangjun Lin1,2, Timothy Gilbertson2
1Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL, United States, 2Department of Internal Medicine, College of Medicine, University of Central Florida, Orlando, FL, United States

P259
Don Tucker Finalist: Activation Of The Sour Receptor Otop1 By Ammonium Chloride, A Key Component Of Salty Licorice
Ziyu Liang1,2, Courtney Wilson3, Bochuan Teng1,2,4, Sue Kinnamon3, Emily Liman1
1Section of Neurobiology, Department of Biological Sciences, University of Southern California, Los Angeles, CA, United States, 2Program in Neuroscience, University of Southern California, Los Angeles, CA, United States, 3Department of Otolaryngology, University of Colorado Medical School, Aurora, CO, United States, 4Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, United States

P261
The KAtp Channel Component Of The Oral Metabolic Signaling Pathway Affects Glucose Taste In Vivo And Glucose Signaling In Vitro
Emily C. Hanselman1, Anilet Tharpe2, Linda J. Flammer2, Mehmet H. Ozdener2, Masafumi Jyotaki2, Karen K. Yee2, Robert F. Margolskee2, Paul A.S. Breslin1,2
1Rutgers University, New Brunswick, NJ, United States, 2Monell Chemical Senses Center, Philadelphia, PA, United States

P263
"Longitudinal Assessment Of Subjective And Objective Changes In Olfactory Function Following Sars-Cov-2 Infection: A Focus On Odor Identification, Intensity, And General Smell Function"
Beyzanur Ergun2, Alefiya D. Albers2, Colin G. Magdamo2, Alysa M. Alejandro Soto2, Andreas Runde2, Mark W. Albers2
1Massachusetts General Hospital , Boston, MA, United States, 2Endicott College, Beverly, MA, United States, 3Massachusetts General Hospital , Boston, MA, United States, 4Massachusetts General Hospital , Boston, MA, United States, 5Massachusetts General Hospital , Boston, MA, United States, 6Massachusetts General Hospital , Boston, MA, United States

P265
A Life Without Smell: Olfactory Function In People Working In Odorless Rooms
Thomas Hummel1, Anika Boesen1, Falk-Tony Olesch1, Ben chen1,2
1Smell & Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany, 2Geriatric Neuroscience Center, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China

P267
Comparison Of Patient Characteristics And Olfactory Sensitivity For Trigger Odorants In Parosmia And Phantosmia
Anna Kristina Hernandez1,2,3, Rumi Sekine1,4, Clara Overbeck1, Marlise K Hofer5, Eri Mori4, Antje Hähner1, Thomas Hummel1
1Smell and Taste Clinic, Department of Otorhinolaryngology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany, 2Department of Otolaryngology - Head and Neck Surgery, Philippine General Hospital, University of the Philippines - Manila, Manila, Philippines, 3Department of Otolaryngology - Head and Neck Surgery, Asian Hospital and Medical Center, Muntinlupa, Philippines, 4Department of Otorhinolaryngology, Jikei University School of Medicine, Tokyo, Japan, 5Department of Psychology, University of British Columbia, British Columbia, Canada, British Columbia, BC, Canada

P269
Investigating Inflammatory Modulation Of Olfactory Sensory Neurons And Immune Cell Populations In The Main Olfactory Epithelium
Ryan E. Owens1,2,4, Varun Haran3,, Chinyi Chu4,, Julian P. Meeks3,, Regina K. Rowe3,
1Department of Environmental Medicine, Rochester, NY, United States, 2Toxicology Graduate Program , Rochester, NY, United States, 3Department of Neuroscience, Rochester, NY, United States, 4Department of Pediatrics , Rochester, NY, United States, 5University of Rochester Medical Center, Rochester, NY, United States

P271
Subjective Impairment Decreases Significantly Over Time In Patients With Olfactory Disorders: A Cohort Study
Antje Welge-Lüssen1, Simon Wirth1, Simona Negoias1, Jan Roth 2, Thomas Hummel3
1Dept. of Otorhinolaryngology, University Hospital Basel, Basel , Switzerland, 2epidemos, Basel, Switzerland, 3Department of Otorhinolaryngology, Interdisciplinary Center Smell & Taste, Medical Faculty Carl Gustav Carus , Dresden, Germany



Saturday, April 20, 2024


7:30 - 9:00 AMEstero Foyer
Continental Breakfast

8:00 - 10:00 AMEstero Ballroom
Poster Session V

P300
Don Tucker Finalist: Poor Olfaction And Risk Of Stroke In Older Adults: The Atherosclerosis Risk In Communities (Aric) Neurocognitive Study
Keran W. Chamberlin1, Chenxi Li1, Anna Kucharska-Newton2, Zhehui Luo1, Mathew Reeves1, Jayant M. Pinto3, Srishti Shrestha4, Jennifer Deal5, Vidya Kamath6, Priya Palta7, David Couper8, Thomas Mosley4, Honglei Chen1
1Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI, United States, 2Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, 3Section of Otolaryngology-Head and Neck Surgery, Department of Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, IL, United States, 4The Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS, United States, 5Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States, 6Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States, 7Department of Neurology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, 8Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States

P302
Myeloid Cell Dysregulation And Eicosanoid Overproduction Define Distinct Endotypes Of Chronic Covid19 Chemosensory Dysfunction
Dante Minichetti1, Amelia Boyd1, Jonathan Hacker1, Caitlin Wong1, Evan Lemire2, Wenjiang Deng2, Kathleen M. Buchheit1, Stella E. Lee3, Rachel E. Roditi3, Reagan w. Bergmark3, Adam L. Haber2, Tanya M. Laidlaw1, Lora Bankova1
1Division of Allergy and Clinical Immunology, Jeff and Penny Vinik Center for Allergic Disease Research, Brigham & Women’s Hospital and Department of Medicine, Harvard Medical School, Boston, MA, United States, 2Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, United States, 3Division of Otolaryngology-Head and Neck Surgery, Brigham and Women's Hospital and Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Boston, MA, United States

P304
Factors Determining Olfactory Function Within The Adult General Population: Findings From The Chris Study
Johannes Frasnelli1,2, Martin Gögele3, David Emmert3, Christian Fuchsberger3
1Department of Anatomy, UQTR, Trois-Rivieres, QC, Canada, 2Research Center, Sacré-Coeur Hospital, Montreal, QC, Canada, 3Institute for Biomedicine, EURAC, Bozen, Italy

P306
Comparing The Number Of Cribriform Plate Foramina In Patients With Acquired And Congenital Anosmia
Jerry Hadi Juratli1, Brigit High1,2, Akshita Joshi1, Eren Yilmaz3, Duzgun Yildirim4, Aytug Altundag5, Thomas Hummel1
1Smell and Taste Clinic, Department of Otorhinolaryngology, Technical University of Dresden, Dresden, Germany, 2Department of Cell and Developmental Biology, Rocky Mountain Taste and Smell Center, University of Colorado School of Medicine, Aurora, CO, United States, 3Istanbul Gelisim University, Faculty of Health Sciences, Istanbul, Turkey, 4Acibadem University, Vocational School, Istanbul, Turkey, 5Pituitary Research Center, Neurosurgery Department, Kocaeli University, Kocaeli, Turkey

P308
Using Novel &Ldquo;Smell-Aids&Rdquo; To Improve Olfactory Function In Patients With Broad Etiologies Including Long Covid: A Clinical Trial
Veronica L. Formanek, Barak Spector, Zachary T. Root, Zhenxing Wu, Kai Zhao
The Ohio State University: Department of Otolaryngology - Head & Neck Surgery, Columbus, OH, United States

P310
Enhancing Preclinical Alzheimer Cognitive Composite (Pacc) Via Olfactory Testing
Qing X Yang, Prasanna Karunanayaka, , Biyar Ahmed, Rommy Elyan, Ren Pang
Penn State College of Medicine, Hershey, PA, United States

P312
Impact Of Aging And Apolipoprotein E4 On Mitral Cells In The Mouse Olfactory Bulb
Dan Zhao, Syed Islam, Shaolin Liu
University of Georgia, Athens, GA, United States

P314
Cross-Cultural Evaluation Of Olfactory Dysfunction: Insights From A Bilingual Longitudinal At-Home Smell Test
Alysa M. Alejandro Soto, Alefiya Albers, Colin Magdamo, Beyzanur Ergun, Andreas Runde, Mark Albers
Department of Neurology, Massachusetts General Hospital

P316
Unveiling The Olfactory Function Spectrum: Linking University Of Pennsylvania Smell Identification Test (Upsit) Scores To Subjective Evaluations
Shima T. Moein1,2, Rafa Khan1, Richard L. Doty1,2
1Smell and Taste Center, Perelman School of Medicine, Philadelphia, PA, United States, 2Research & Development Division, Sensonics International, Haddon Heights, NJ, United States

P318
Evaluating The Burden Of Smell Loss On General Health And Well-Being
Vicente Ramirez, Valentina Parma
Monell Chemical Senses Center, Philadelphia, PA, United States

P320
Long-Term Impacts Of Covid-19 On Multiple Sensory Systems: A Preliminary Report
Ahmad Odeh1, Veronica Formanek1, Megan Kobel1, Jessica Lewis1, Aaron Moberly2, Dan Merfeld1, Christopher Simons3, Kai Zhao1
1Ohio State University Department of Otolaryngology, Columbus, OH, United States, 2Department of Otolaryngology - Head & Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, United States, 3Ohio State University, College of Food, Agricultural, and Environmental Sciences, Columbus, OH, United States

P322
Importance Of Olfaction Throughout Lifespan In Scotland And Pakistan
Agnieszka Sorokowska1, Michal Misiak1,2, S. Craig Roberts2,3, Piotr Sorokowski1
11Institute of Psychology, University of Wrocław, Wroclaw, Poland, 2Being Human Lab, University of Wrocław, Wroclaw, Poland, 3Department of Psychology, University of Stirling, Stirling, United Kingdom

P324
The Birthrates Of Olfactory Sensory Neurons That Express Specific Odorant Receptors Are Accelerated By Discrete Odors.
Kawsar Hossain, Madeline Smith, Stephen Santoro
University of Colorado, Anschutz Medical Campus, Aurora, CO, United States

P326
A Cross-Species Comparison Of The Nasal Microenvironment
Pia LaPorte1, Ludmila Globa1, Oleg Pustovyy1, Melissa Singletary1,2
1Department of Anatomy, Physiology, and Pharmacology, College of Veterinary Medicine, Auburn University, AL, 2Canine Performance Sciences Program, College of Veterinary Medicine, Auburn University, AL

P328
The Role Of Trpa1 And Trpv1 On Astringency Perception In Humans
Kevin Kim, Christopher Simons
The Ohio State University, Columbus, OH, United States

P330
Relationship Between 6-N-Propylthiouracil (Prop) Bitterness, Prop Taster Status, Bitter Taste Receptor Gene Tas2R38 (Rs713598), And Taste Qualities Of Ferrous Sulfate And Copper Sulfate.
Sasi Tansaraviput, Alissa A. Nolden
University of Massachusetts, Amherst, MA, United States

P332
How Sweet Is It? Sex-Related Differences In Sweetness Perception Of Habitual And Non-Habitual Consumers Of Low-Calorie Sweeteners.
Stephanie Okoye1, Sara Petty2, Yanina Pepino1,2,3
1Division of Nutritional Sciences University of Illinois Urbana-Champaign, Urbana, IL, United States, 2Food Science and Human Nutrition University of Illinois Urbana-Champaign, Urbana, IL, United States, 3Carle Illinois College of Medicine, Urbana, IL, United States

P334
Functional Localization Of The Primary Taste Cortex In The Anesthetized Macaque Monkey
Renée Hartig1, Ali Karimi2, Henry Evrard3
1Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, United States, 2New York University, New York, NY, United States, 3International Center for Primate Brain Research, Shanghai, China

P336
Don Tucker Finalist: Dopaminergic Modulation Of Cortical Motor Circuits During Gustatory Sensorimotor Transformation
John Chen1,2, Alfredo Fontanini1,2
1Program in Neuroscience, Stony Brook, NY, United States, 2Department of Neurobiology and Behavior, Stony Brook, NY, United States

P338
The Role Of Component Reliability In Behavioral And Neural Response To Bimodal Flavor Mixtures
Isabella B Allar, Alex Hua, Joost X Maier
Wake Forest School of Medicine, Winston-Salem, NC, United States

P340
Olfactory Biomarkers Associated With Brain Volumes And Cognition In Former Professional American Football Players: Results From The Harvard Football Players Health Study
Benoit Jobin1,2, Colin Magdamo2,3, Rachel Grashow4, Ona Wu2,3,5, Coby Dodelson2,5, Grant L Iverson2,3,6, Ross Zafonte2,3,6, Aaron L Baggish2, Mark W Albers2,3
1Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada, 2Massachusetts General Hospital, Boston, MA, United States, 3Harvard Medical School, Boston, MA, United States, 4Harvard T. H. Chan School of Public Health, Boston, MA, United States, 5Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA, United States, 6Spaulding Rehabilitation Hospital, Charlestown, MA, United States

P342
Neural Processing Of Oral Thermal Stimuli In The Somatosensory Cortex
Morgan Shakeshaft, Roberto Vincis
Florida State University, Tallahassee, FL, United States

P344
Metastable Dynamics In Gustatory Cortex During Taste Mixture-Based Perceptual Decision-Making
Liam Lang1,2,3, Jennifer Blackwell2,3, Yuejiao Zheng1,2, Giancarlo La Camera1,2,3, Alfredo Fontanini1,2,3
1Program in Neuroscience, Stony Brook University, Stony Brook, NY, United States, 2Center for Neural Circuit Dynamics, Stony Brook University, Stony Brook, NY, United States, 3Department of Neurobiology & Behavior, Stony Brook University, Stony Brook, NY, United States

P346
Insulin Modulates Excitatory Drive Of Pyramidal Neurons In The Posterior Piriform Cortex.
Vaibhav R. Konanur, Celine Sanluecha, Lindsay R. Vivona, Joseph D. Zak
University of Illinois at Chicago, Chicago, IL, United States

P348
Fast Updating Feedback From The Piriform Cortex To The Olfactory Bulb Relays Multimodal Identity And Reward Contingency Signals During Rule-Reversal
Diego E Hernandez Trejo1, Andrei Ciuparu2, Pedro Garcia da Silva3, Cristina M Velazquez Cobos4, Benjamin Rebouillat5, Michael Gross1, Honggoo Chae1, Martin B Davis 1, Raul C Mureşan2,6, Dinu F Albeanu1,7
1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, United States, 2Transylvanian Institute of Neuroscience, Cluj-Napoca, Rumania, 3Champalimaud Foundation, Lisbon, Portugal, 4Oxford University, London, United Kingdom, 5Université Paris 8 Vincennes - Saint-Denis, Paris, France, 6STAR-UBB Institute, Babeş-Bolyai University, Cluj-Napoca, Rumania, 7School for Biological Sciences, CSHL, Cold Spring Harbor, NY, United States

P350
Longitudinal Analysis Of Taste Representational Drift In The Gustatory Cortex
Martin A Raymond, John D Boughter, Max L Fletcher
University of Tennessee Health Science Center

P352
Quiescent Horizontal Basal Stem Cells Act As A Niche For Olfactory Neurogenesis In A 3D Organoid Model
Juliana Gutschow Gameiro1,2, James E Schwob3, Eric H Holbrook3,4, Marco Aurelio Fornazieri5, Brian Lin3
1Department of Clinical Surgery, State University of Londrina, Paraná, Londrina, Brazil, 2Health Sciences Graduate Program, State University of Londrina, Paraná, Londrina, Brazil, 3Department of Developmental, Molecular and Chemical Biology, School of Medicine, Tufts University, Boston, MA, United States, 4Department of Otolaryngology-Head & Neck Surgery, Massachusetts Eye and Ear, Boston, MA, United States, 5Department of Medicine, Pontifical Catholic University of Paraná, Paraná, Londrina, Brazil

P354
Exploring Odor-Evoked Activity In Diagonal Band Cholinergic Neurons In Awake Mice.
Kelsey Glasper, Max Fletcher
University of Tennessee Health Science Center, Memphis, TN, United States

P356
Incidental And Reinforced Olfactory Learning In The Newborn Rabbit: Differential Involvement Of Endocannabinoid And Noradrenergic Systems
Gerard Coureaud1, Eva-Gunnel Ducourneau2, Nina Colombel1, Patricia Duchamp-Viret1, Guillaume Ferreira2
1Lyon Neuroscience Research Center (CRNL), ENES team, Lyon, France, 2Nutrition and Integrative Neurobiology lab (NutriNeuro), FoodCircus team, Bordeaux, France

P358
Neophobia Attenuation Is Linearly Correlated To The Magnitude And Fidelity Of Neuronal Signaling In Gustatory Cortex
Walter J Krueger, Martin A Raymond, John D Boughter Jr., Max L Fletcher
Department of Anatomy and Neurobiology, Integrated Biomedical Sciences Program, College of Graduate Health Sciences, University of Tennessee Health Science Center, Memphis, TN, United States

P360
Latent Enhancement Of Aversion Learning Following Benign Taste Experience Requires Basolateral Amygdala Activity
Veronica Flores1, Jackson Chew1, Donald Katz2, Jian-You Lin2
1Furman University, Greenville, SC, United States, 2Brandeis University, Waltham, MA, United States

P362
The Impact Of Innocuous Taste Experience On Long-Term Taste Learning And Memory Persistence
Dallas Shuman, Kadence Alexander, Veronica Flores
Furman University, Greenville, SC, United States

P364
Parallel Genetically-Distinct Basal Amygdala Pathways Route Affective Information To Ventral Striatum Subregions
Sarah E Sniffen1, Sang Eun Ryu1, Milayna M Kokoska1, Janardhan Bhattarai2, Yingqi Wang2, Ellyse R Thomas1, Graylin M Skates1, Natalie L Johnson1, Andy Chavez1, Sophia Iaconis1, Daisy Valle1, Minghong Ma2, Daniel W Wesson1
1Department of Neuroscience and Department of Pharmacology and Therapeutics, Center for Smell and Taste, University of Florida, Gainesville, FL, United States, 2Department of Neuroscience, University of Pennsylvania, Philadelphia, PA, United States

P366
Using External And Self-Generated Olfactory Cues As Landmarks To Learn A Spatial Goal By Drosophila Melanogaster
Yang Chen1,2, Robert Alfredson2, Ulrich Stern2, Dorsa Motevalli2, Sydney Fogleman2, Chung-Hui Yang2
1Dept. Biology, Duke University, Durham, NC, United States, 2Dept. Neurobiology, Duke University Medical School, Durham, NC, United States

P368
Employing Two-Photon Imaging And Holographic Stimulation To Probe The Cellular Basis Of Odor Engrams In The Hippocampus.
Kira A. Steinke, Gregory Futia, Connor McCullough, Emily A. Gibson, Diego Restrepo
University of Colorado Anschutz Medical Campus, Aurora, CO, United States

P370
Trpm8 Participates In Conditioned Preferences For Oral And Ingesta Temperatures In Mice
Kyle T. Zumpano, Christian H. Lemon
University of Oklahoma, Norman, OK, United States

P372
Charaterization Of Gastrin Releasing Peptide Receptor Neurons In The Gustatory Cortex And Their Role In Modulating Eating Behavior
Maria Isaac1,2, Carlo Fontanini1, Arianna Maffei1,2
1Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, NY, United States, 2Graduate Program in Neuroscience, Stony Brook University, Stony Brook, NY, United States

P374
Sequential Activity Of Ca1 Hippocampal Cells Constitutes A Temporal Memory Map For Associative Learning In Mice
Ming Ma1, Fabio Simoes de Souza1,2, Gregory L. Futia3, Sean R. Anderson4, Jose Riguero4,5, Daniel Tollin4,5, Arianna Gentile-Polese1, Jonathan P. Platt6, Kira Steinke7, Naoki Hiratani8, Emily A. Gibson3,5, Diego Restrepo1,5
1Department of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 2Center for Mathematics, Computation and Cognition, Federal University of ABC, Sao Bernardo do Campo, Brazil, 3Department of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 4Department of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 5Neuroscience Graduate Program, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 6Department of Neurosurgery, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 7Integrated Physiology Graduate Program, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 8Department of Neuroscience, Washington University, St. Louis, MO, United States

9:00 - 10:00 AMEstero Foyer
Coffee Break

10:00 - 12:00 PMCalusa EFGH
Olfaction and Taste: Biomarkers for Health

Chair(s): Valentina Parma
10:00
Olfaction And Taste: Biomarkers For Health
Valentina Parma1, Katie Boateng2, Nancy Rawson1
1Monell Chemical Senses Center, Philadelphia, PA, United States, 2Smell and Taste Association of North America, Philadelphia, PA, United States

10:02
Taste And Smell Dysfunction In Wolfram Syndrome, A Genetic Model For Diabetes And Neurodegenerative Diseases
M. Yanina Pepino1,2, Raul Alfaro1, Tamara Hershey3,4, Jessica Nicanor-Carreón2
1Department of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 2Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 3Department of Psychiatry, School of Medicine, Washington University, St Louis, MO, United States, 4Department of Radiology, School of Medicine, Washington University, St Louis, MO, United States

10:27
Smell And Taste Changes In Children With Cancer: No &Ldquo;One-Size-Fits-All&Rdquo; Solution
Mirjam van den Brink1,2, Wim J.E. Tissing1,3, Marta Fiocco1,4,5, Remco C Havermans2
1Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands, 2Laboratory of Behavioural Gastronomy, Centre for Healthy Eating and Food Innovation, Maastricht University Campus Venlo, Venlo, Netherlands, 3Department of Pediatric Oncology and Hematology, University of Groningen, Beatrix Children’s Hospital, University Medical Center Groningen, Groningen, Netherlands, 4Mathematical Institute, Leiden University, Leiden, Netherlands, 55Medical Statistics, Department of Biomedical Data Science, Leiden University Medical Center, Leiden, Netherlands

10:45
Taste And Smell Dysfunction In Individuals At Risk For Alcohol Use Disorder: A Study Of The 2013-2014 Us National Health And Nutrition Examination Survey (Nhanes)
Khushbu Agarwal1,2, Tanique Schaffe-Odeleye1,2, Marinza Marzouk1,2, Paule V Joseph1,2
1Section of Sensory Science and Metabolism, National Institute on Alcohol and Alcoholism, Bethesda, MD, United States, 2National Institute of Nursing Research, BETHESDA, MD, United States

11:10
Chemosensory Dysfunction In Anxiety: Usable Clinical Information?

Wen Li
University of Texas Health Science Center-Houston, Houston, TX, United States

11:35
Smell In Aging: When To Start Testing For Neurodegeneration?
Claire Murphy1,2, Paul Wheeler1
1San Diego State University, San Diego, CA, United States, 2University of California, San Diego, La Jolla, CA, United States

10:00 - 12:00 PMCalusa ABC
The Brainstem: Transforming chemosensation to behavior

Chair(s): Hojoon Lee
10:00
The Brainstem: Transforming Chemosensation To Behavior
Hojoon Lee
Northwestern University, Evanston, IL, United States

10:02
Central Circuit For Taste-Dependent Salivation
Gyujin Park, Jiahao Ye, Hojoon Lee
Department of Neurobiology, Northwestern university, Evanston, IL, United States

10:27
Parabrachial Cgrp Neurons Affect Taste-Guided Behaviors
Neville Ngum, Jinrong H Li, Kyle T Zumpano, Catori J Roberts, Traci L Redwine, Damilola V Adesina, Christian H. Lemon
University of Oklahoma, Norman, OK, United States

10:45
Functional Architecture In The Interoceptive Brainstem
Chen Ran1,2, Jack C. Boettcher2, Judith A. Kaye2, Catherine E. Gallori1,2, Yandan Wang2, Stephen D. Liberles2
1Department of Neuroscience, Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, CA, United States, 2Department of Cell Biology and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, United States

11:10
Area Postrema Neurons Mediate Interleukin-6 Function In Cancer-Associated Cachexia
Bo Li1,2
1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, United States, 2Westlake University, Hangzhou, China

11:35
A Role For The Locus Coeruleus In The Modulation Of Feeding And Taste
Will Fan1, Natale Sciolino1-4
1Department of Physiology and Neurobiology, 2Department of Biomedical Engineering, 3Department of Psychological Sciences, 44Institute for the Brain and Cognitive Sciences, University of Connecticut, Storrs, CT, 06269, USA

12:00 - 1:00 PMLunch On Own
Lunch on Own

1:00 - 3:00 PMCalusa EFGH
Nutrient Sensing, Learning and Reward

Chair(s): Kathryn Deibler and Linda Flammer
1:00
Introduction
Kathryn Deibler

1:02
Re-Thinking Food Reward: Is “Deliciousness” A Cause Of The Obesity Epidemic Or A Solution To It?
Mark Schatzker
Yale University

1:27
Evidence That Human Oral Glucose Detection Involves A Sweet Taste Pathway And A Glucose Transporter Pathway
Linda Flammer
Monell Chemical Senses Center

1:45
Brain Networks Underlying Hunger And Reward
Sam Bacharach
Monell Chemical Senses Center

2:10
Non-Canonical Roles For Endogenous Opioids In Affect, Motivation, And Metabolism
Daniel C. Castro
Washington University in St. Louis

2:35
The Inherent And Learned Factors For Consumer Selection Of Macronutrient-Rich Foods
Jing Zhou
Ingredion

1:00 - 3:00 PMCalusa ABC
Clinical impact on damage to chemosensory pathways.

Chair(s): Robert Pellegrino
1:00
Taste Loss And Flavor Perception
Linda M. Bartoshuk1, Derek J. Snyder1,2
1University of Florida, Gainesville, FL, United States, 2Amerian Psychological Association, Washington, DC, United States

1:30
Taste Loss And Burning Mouth Syndrome
Derek J. Snyder1,2, Miriam Grushka3, Linda M. Bartoshuk1
1University of Florida, Gainesville, FL, United States, 2Amerian Psychological Association, Washington, DC, United States, 3William Osler Health Centre, Toronto, Canada

2:00
Trigeminal Function After Damage Of The Olfactory System Or Other Neuronal Structures
Thomas Hummel
Smell & Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Dresden, --, Germany

2:30
Scents And Circuits: Can Odorants Modulate The Extended Amygdala And Combat Sudden Unexpected Death In Epilepsy (Sudep)?
William Nobis
Vanderbilt University Medical Center, Nashville, TN, United States

3:00 - 3:30 PMCalusa Foyer
Coffee Break

3:30 - 5:00 PMCalusa EFGH
DEIB Lecture

Building Your Scientific Clan By Nurturing Diversity And Mentorship - Sharing Insights From My Journey
M. Yanina Pepino
University of Illinois at Urbana-Champaign

5:00 - 6:00 PMEstero Foyer
Diversity Networking Reception (Invite Only)

5:00 - 7:00 PMDinner On Own
Dinner on Own

7:00 - 9:00 PMCalusa EFGH
President's Symposium: Regenerative Medicine and the Senses

Chair(s): Paul Breslin
7:00
Regenerative Medicine And The Senses
Paul Breslin1,2
1Rutgers University, New Brunswick, NJ, USA, 2Monell Chemical Senses Center, Philadelphia, PA, USA

7:05
The Sense Of Taste Is Reliable Until It’S Not: The Myriad Impacts Of Cancer Therapies On Taste Bud Homeostasis
Linda Barlow
Department of Cell and Developmental Biology and the Rocky Mountain Taste and Smell Center, University of Colorado Anschutz Medical Campus, Aurora CO USA

7:30
Inflammatory Cytokines In Taste Loss And Regeneration
Hong Wang
Monell Chemical Senses Center, Philadelphia, PA, USA

7:55
How To Fix A Broken Nose
James E Schwob
Tufts University School of Medicine, Boston, MA, United States

8:20
Reprogramming By Drug-Like Molecules In Hair Cell Regeneration In The Mature Inner Ear
Zheng-Yi Chen
Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School and Mass Eye & Ear, Boston MA, USA

9:00 - 12:00 AMMangroves & Belvedere
AChemS Closing Dance Party