Conference Program

Welcome! Please find the current preliminary program for AChemS 2025 listed below. Note that any aspect of this program is subject to change.

April 23 (10:00 AM - 4:00 PM): Pre-Meeting
April 23-26: AChemS Annual Meeting Program

Wed - Apr 23

Thu - Apr 24

Fri - Apr 25

Sat - Apr 26

View Summary Only | Show Only 1st Author

FRIDAY, APRIL 25

7:30 - 9:00 AM BREAKFAST

CONTINENTAL BREAKFAST Estero Foyer

8:00 - 10:00 AM POSTER SESSION

POSTER SESSION III (click to view) (click to close) Estero Ballroom

SOCIAL BEHAVIOR

200

A NATURAL LESION MODEL UNRAVELS THE NATURE OF CHEMICAL FEAR COMMUNICATION Jasper H. B. de Groot. Behavioural Science Institute, Radboud University, Nijmegen, Netherlands

202

CHILD FOOD NEOPHOBIA AND SYMPATHETIC AROUSAL IN RESPONSE TO ODOR EXPOSURE Agnieszka Sorokowska1, Anna Oleszkiewicz1, 2, Sabina Barszcz1, Dominika Chabin1, Aleksandra Kamie?ska1, Piotr J?drusik1, ?ukasz Kaczmarek3, Piotr Sorokowski1, Thomas Hummel2. 1Institute of Psychology, University of Wroc?aw, Wroclaw, Poland. 2Smell and Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany. 3Department of Psychology and Cognitive Science, Adam Mickiewicz University in Poznan, Poznan, Poland

204

CHEMOSENSORY DETECTION OF PREDATOR-DERIVED KAIROMONES AND ASSOCIATED BEHAVIOR IN MICE Jinxin Wang, Varun Varun, Julian Meeks. Department of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA

206

COOKING ODORS, BUT NOT FOOD CONSUMPTION, INFLUENCE BODY ODORS AND SOCIAL JUDGMENTS Jessica Gaby1, Pete Hatemi2, Helene Hopfer2. 1Middle Tennessee State Univeristy, Murfreesboro, TN, USA. 2Penn State University, State College, PA, USA

208

THE IMPACT OF SMELLING HEXADECANAL ON STARTLE RESPONSE IN MEN AND WOMEN Juna Khatib, Tali Weiss, Ofer Perl, Noam Sobel. Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel

TASTE DISORDER

210

EXPRESSION OF FAMILIAL DYSAUTONOMIA-CAUSING GENE ELP1 IN THE PERIPHERAL TASTE SYSTEM IS IMPORTANT FOR THE DEVELOPMENT OF TASTE PAPILLAE AND BUDS Md Mamunur Rashid1, Wenxin Yu1, Ruchi Sha1, Zhonghou Wang1, Frances Lefcort2, Hong-Xiang Liu1. 1Regenerative Bioscience Center, Department of Animal and Dairy Science, University of Georgia, Athens, GA, USA. 2Department of Microbiology and Cell Biology, Montana State University, Bozeman, MT, USA

212

GLP-1 RECEPTOR AGONISTS SIGNIFICANTLY IMPAIR TASTE FUNCTION Richard Doty, Rafa Khan. University of Pennsylvania, Philadelphia, PA, USA

214

SARS-COV-2 INFECTION OF TASTE BUD CELLS IN HUMAN ACE2 TRANSGENIC MICE Kang-Hoon Kim1, Emma Larsson1, Heaven Branch1, Richard Bowen2, Hong Wang1. 1Monell Chemical Senses Center, Philadelphia, PA, USA. 2Departments of Biomedical Sciences, Colorado State University, Fort Collins, CO, USA

TASTE PREFERENCE

216

BITTER MATERNAL DIET INCREASES OFFSPRING BITTER ACCEPTANCE IN 24-HR FEEDING TRIALS BUT NOT BRIEF-ACCESS TASTE TESTS Verenice Ascencio Gutierrez1, Samantha L Brooker1, Kamila D Nixon1, Emily Demieri1, Jyothi Vasavan1, Ann-Marie Torregrossa1, 2. 1Department of Psychology, University at Buffalo, Buffalo, NY, USA. 2Center for Ingestive Behavior Research, University at Buffalo, Buffalo, NY, USA

218

ROLE OF THE ARYL HYDROCARBON RECEPTOR IN TASTE CELLS Salin Raj Palayyan, Sunil K Sukumaran. Department of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, NE, USA

220

CONSUMER-AFFORDABLE PRACTICES FOR REDUCING SODIUM INTAKE: INSIGHTS FROM THE SAL&MIEUX PROJECT ON DISCRETIONARY SALT Thierry Thomas-Danguin1, Raphael Monod1, 2, 3, Sylvie Clerjon2, 3. 11Centre des Sciences du Gout et de l'Alimentation, INRAE, CNRS, Institut Agro, Universite Bourgogne Europe, Dijon, France. 2Univ Clermont Auvergne, INRAE, UR QuaPA, St Genes Champanelle, France. 3INRAE, PROBE Research Infrastructure, AgroResonance Facility, St Genes Champanelle, France

222

BEHAVIORAL EFFECTS OF CHEMOGENETICALLY SILENCING MOUSE PERIPHERAL TASTE PROCESSING Kathleen Depina1, Steven St. John2, Nirupa Chaudhari1, 3. 1Department of Physiology a Biophysics, University of Miami Miller School of Medicine, Miami, FL, USA. 2Department of Psychology, Rollins College, Winter Park, FL, USA. 3Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL, USA

224

NEOPHOBIA TO SACCHARINE ATTENUATED BY ONLY BRIEF EXPOSURE Avi P Patel, Griffin McFarland, Donald B Katz. Brandeis University, Waltham, MA, USA

226

MECHANISM OF SWEET TASTE PLASTICITY IN RESPONSE TO A HIGH-SUGAR DIET Hayeon Sung, Monica Dus. University of Michigan, Ann Arbor, MI, USA

228

THE ROLE OF STIMULUS TEMPERATURE ON SALT PERCEPTION AND CENTRAL GUSTATORY REPRESENTATION IN BEHAVING MICE Mariela E. Marques1, Elise Frierson2, Katherine O. Odegaard2, Cecilia G. Bouaichi1, Roberto Vincis3. 1Department of Biological Sciences and Program in Neuroscience, Florida State University, Tallahassee, FL, USA. 2Department of Biological Sciences, Florida State University, Tallahassee, FL, USA. 3Department of Biological Sciences, Program in Neuroscience, and Molecular Biophysics, Florida State University, Tallahassee, FL, USA

230

ACCURACY AND TEMPORAL PRECISION OF OPEN-SOURCE MACHINE LEARNING MODELS FOR LICK DETECTION Georgia R. Davis1, 2, Mia B. Fox1, Max L . Fletcher1, John D. Boughter Jr. 1. 1Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, USA. 2Undergraduate, Rhodes College, Memphis, TN, USA

232

FATTY ACID PREFERENCE DIFFERS BETWEEN OB/OB AND WT MICE Nicholas Amado1, Judith Storch1, Paul AS Breslin1, 2. 1Rutgers University, New Brunswick, NJ, USA. 2Monell Chemical Senses Center, Philadelphia, PA, USA

234

THE ROLE OF TRPM8 THERMORECEPTORS AND TEMPERATURE IN SWEET TASTE PREFERENCES IN MICE Kyle T. Zumpano, Neville M. Ngum, Mehrnoush Nourbakhsh_Rey, Christian H. Lemon. University of Oklahoma, Norman, OK, USA

236

THE ROLE OF TRPM8 FUNCTION IN THERMOSENSORY EFFECTS ON GLUCOSE TASTE PREFERENCES IN MICE Mehrnoush Nourbakhsh-Rey, Neville M. Ngum , Christian H. Lemon. The University Of Oklahoma, Norman, OK, USA

238

OSMOTIC AND DEHYDRATION CHALLENGES SHAPE EARTHWORM BEHAVIOR IN THEIR SOIL ENVIRONMENT. Jonathan G Mebrahtu 1, Folashaye E Araromi 1, Ameena A Mohassib 1, Laura Ortega-Damian 1, Diana M Quiroz-Ruiz 1, Tania C Romero1, Rebeca V Rodriguez 2, Cecil J Saunders 1, 2. 1Department of Biological Sciences, Kean University, Union, NJ, USA. 2School of Integrative Science and Technology, Kean University, Union, NJ, USA

240

LONG-TERM SUGAR EXPOSURE INCREASES THE CONSUMPTION FOR GLUCOSE OVER FRUCTOSE IN BOTH C57BL/6J AND T1R2+3KO MICE David W. Pittman1, Tatiyana L. Adkins1, Mackenzie L. Clinch1, Riley B. Gettys1, Lindsey A. Schier2. 1Wofford College, Spartanburg, SC, USA. 2University of Southern California, Los Angeles, CA, USA

242

TASTE CHANGES IN A RAT MODEL OF SPINAL CORD INJURY: IMPACT OF HIGH FAT DIET AND WEIGHT LOSS SURGERY Jonathan W. Snyder, Tiffany Tang, Nelli Horvath, Gregory M. Holmes, Andras Hajnal. Penn State College of Medicine, Hershey, PA, USA

244

TASTE-TASTE AND CROSS-MODAL INTERACTIONS IN A REAL FOOD SYSTEM Ashley L Gruman, Helene Hopfer, John E Hayes. The Pennsylvania State University Food Science Department, University Park, PA, USA

OLFACTORY BULB

246

ODOR SPECIFIC ACTIVATION PATTERNS IN THE HUMAN OLFACTORY BULB DETECTED BY HIGH RESOLUTION BOLD FMRI ON 7 TESLA Xinyi Zhou1, 2, 3, Adrian G. Paez1, 2, Gaoqiang Xu1, 2, Yu Luo1, 2, Xinyuan Miao4, Peter C. M. Van Zijl1, 2, Arnold Bakker5, 6, Vidyulata Kamath6, Jun Hua1, 2. 1Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. 2F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD. 3Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD. 4Department of Radiology, Johns Hopkins Hospital, Baltimore, MD. 5Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD. 6Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD

248

IN VIVO DYNAMICS OF DOPAMINERGIC CIRCUITS IN THE MOUSE OLFACTORY BULB Priscilla Ambrosi, Elizabeth Moss. Oregon Health a Science University, Portland, OR, USA

250

ODOR CONCENTRATION AND PERCEIVED ODOR INTENSITY PROCESSING WITHIN AND BETWEEN THE HUMAN OLFACTORY BULB AND PIRIFORM CORTEX Irene Zanettin1, Frans Norden1, Mikael Lundqvist1, Artin Arshamian1, Johan N. Lundstrom1, 2, 3. 1Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. 2Monell Chemical Senses Center, Philadelphia, PA, USA. 3Department of Otorhinolaryngology, Karolinska Institutet, Stockholm, Sweden

252

HUMAN OLFACTORY BULB BETA ACTIVITY PREDICTS THE GAMMA ACTIVITY OF THE FOLLOWING SNIFF Frans Norden1, Behzad Iravani1, Anja L. Winter1, Mikael Lundqvist1, Artin Arshamian1, Johan N. Lundstrom1, 2, 3. 1Karolinska Institutet, Solna, Sweden. 2Monell Chemical Senses Center, Philadelphia, PA, USA. 3Stockholm University Brain Center, Stockholm, Sweden

254

ANALYZING THE ROLE OF CD11B AND MICROGLIA IN RECOVERY FROM OLFACTORY INJURY David Poore, Nick DeRusha, Diego Rodriguez-Gil. East Tennessee State University, Johnson City, TN, USA

256

OPTOGENETIC STIMULATION OF THE OLFACTORY SENSORY NEURON INPUT TO THE OLFACTORY BULB ELICITS GAMMA ENTRAINMENT OF DORSAL HIPPOCAMPUS IN A MOUSE MODEL OF ALZHEIMER'S DISEASE Joseph A. Villanueva1, 2, Maray Valle3, Ming Ma1, Emily A. Gibson4, Maria A. Nagel5, 6, Diego Restrepo1, 6. 1Department of Cell a Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. 2Department of Neurology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. 3Bioengineering Graduate Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. 4Department of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. 5Department of Ophthalmology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. 6Neuroscience Graduate Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA

258

HETEROGENEOUS MONOTONIC AND NON-MONOTONIC RESPONSES TO ODOR IN MITRAL/TUFTED GLOMERULI OF THE MOUSE OLFACTORY BULB. David Wharton4, Narayan Subramanian1, Bhargav Karamched2, 3, 4, Richard Bertram2, 3, 4, Douglas A Storace1, 2, 3. 1Department of Biological Science, Florida State University, Tallahassee, FL, USA. 2Program in Neuroscience, Florida State University, Tallahassee, FL, USA. 3Institute of Molecular Biophysics, Florida State University, Tallahassee, FL, USA. 4Department of Mathematics, Florida State University, Tallahassee, FL, USA

260

ODOR-SPECIFIC INCREASES IN BOTH SENSITIVITY AND DYNAMIC RANGE IN THE OLFACTORY BULB OF THE MEXICAN CAVEFISH Evan Lloyd, Douglas A. Storace. Florida State University, Tallahassee, FL, USA

262

TRANSCUTANEOUS VAGAL NERVE STIMULATION IN OLFACTORY BULB-RELEVANT FREQUENCIES MODULATE OLFACTORY FUNCTION Andrea Aejmelaeus-Lindstrom1, Anja L Winter1, Gregory Francis2, Artin Arshamian1, Johan N Lundstrom1, 3, 4. 1Karolinska institutet, Stockholm, Sweden. 2Purdue University, West Lafayette, IN, USA. 3Monell Chemical Senses Center, Philadelphia, PA, USA. 4Karolinska University Hospital, Stockholm, Sweden

264

OLFACTORY BULB INHIBITORY INTERNEURONS MODULATE THREAT PERCEPTION IN MICE Sanyukta Pandey, Sharvari Avinash Thorat, Susobhan Das, Lavanya Ranjan, Kevin Thoams, Nixon M. Abraham. Indian Institute of Science Education and Research, PUNE, India

266

THE PERSISTENCE OF CHANGES IN OLFACTORY BULB TAAR4-RELATED CIRCUITS EVOKED BY EARLY POSTNATAL EXPOSURE TO PHENETHYLAMINE (PEA) FOLLOWING OLFACOTRY SENSORY NEURON ABLATION Jordan D. Gregory1, 2, Claire E. Cheetham1. 1Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA. 2Center for Neuroscience at the University of Pittsburgh, Pittsburgh, PA, USA

268

OLFACTORY BULB THETA OSCILLATIONS IN THE ABSENCE OF THETA-RANGE SNIFFING Andrew Sheriff1, Gregory Lane1, Qiaohan Yang1, Naelly Arriaga1, Guangyu Zhou1, Mahmoud Omidbeigi1, Vivek Sagar1, Leslie M. Kay2, Bruce Tan3, Christina Zelano1. 1Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. 2Department of Psychology, Institute for Mind and Biology, University of Chicago, Chicago, IL, USA. 3Department of Otolaryngology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA

270

BEHAVIORALLY RELEVANT FEATURES OF THE NEURAL CODE IN OLFACTORY BULB Saeed Karimimehr1, 2, Sebastian Ceballo1, Mursel Karadas1, Dmitry Rinberg1, 2, 3. 1Neuroscience Institute, New York University Langone Health, New York, NY, USA. 2Center for Neural Science, New York University, New York, NY, USA. 3Department of Physics, New York University, New York, NY, USA

CHEMESTHESIS

272

GENETIC IDENTIFICATION OF A RAPIDLY-ADAPTING LOW-THRESHOLD MECHANORECEPTOR INNERVATING FUNGIFORM PAPILLAE Thomas A. Myers1, 2, Joseph M. Breza2, Robin F. Krimm1. 1University of Louisville, Louisville, KY, USA. 2Eastern Michigan University, Ypsilanti, MI, USA

274

OLFACTORY-TRIGEMINAL INTERACTIONS IN PARKINSON'S DISEASE COMPARED TO OTHERS FORMS OF OLFACTORY DYSFUNCTION Sarah Brosse1, Olivier Fortier-Lebel2, Emilie Hudon2, Johannes Frasnelli1, 3. 1Department of Anatomy, Universite du Quebec a Trois-Rivieres, Trois-Rivieres, QC, Canada. 2Department of Psychology, Universite du Quebec a Trois-Rivieres, Trois-Rivieres, QC, Canada. 3Research Center of the Sacre-Coeur Hospital of Montreal, Montreal, QC, Canada

276

EXAMINING ORTHONASAL AND ORAL TRIGEMINAL RECEPTOR ACTIVATION AND ROLE IN SPICY FOOD PREFERENCES Rebecca S. Estrada, Caitlin M. Cunningham, Theresa L. White. Le Moyne College, SYRACUSE, NY, USA

278

THE EXAMINATION OF ORAL ASTRINGENCY WITH EDIBLE FILM FORMULATIONS Gregory S. Smutzer, Amelia G. Maughan, Zayd Haydar. Department of Biology, Temple University, Philadelphia, PA, USA

280

DIFFERENTIATING NEURAL RESPONSES TO OLFACTORY AND TRIGEMINAL STIMULI USING EEG AND MACHINE LEARNING Johannes Frasnelli1, 2 , Matin Asghar Pour1, Olivier Fortier-Lebel1, Sarah Brosse1, Emilie Hudon1, Anne-Lise Saive3, Jie Mei4. 1Universite du Quebec a Trois-Rivieres, Trois-Rivieres, QC, Canada. 2Sacre-Coeur Hospital, Montreal, QC, Canada. 3Institut Lyfe, Lyon, France. 4IT University, Linz, Austria

282

CAPSAICIN SENSITIZATION DURING CONSUMPTION OF A REAL FOOD IS NON-LINEAR Paige M. Cunningham, John E. Hayes. The Pennsylvania State University, University Park, PA, USA

284

IDENTIFYING MECHANISMS OF ASTRINGENCY TRANSDUCTION Mikaela Murph1, Anisa Seenauth1, Keylin Escobar2, Yalda Moayedi1. 1New York University College of Dentistry, New York, NY, USA. 2Columbia University, New York, NY, USA

286

DETERMINING THE CONTRIBUTION OF INTRANASAL CHEMESTHETIC SENSATION ON ADDICTION. Maria F. Ramirez1, Abhishek Gour2, Emma K Watson1, Abhisheak Sharma2, Daniel Wesson1. 1Department of Pharmacology a Therapeutics, Department of Neuroscience, and Florida Chemical Senses Institute, College of Medicine, Gainesville, FL, USA. 2Department of Pharmaceutics, College of Pharmacy, Gainesville, FL, USA

10:00 - 11:00 AM LECTURE

DIVERSITY, EQUITY, INCLUSION, AND BELONGING (DEIB) LECTURE Calusa EFGH

10:00

YOU ARE WHOLE JUST AS YOU ARE: MORE TO INCLUSION THAN WIDENING THE DOOR Dr. Deana McDonagh1, 2, 3. 1Professor of Industrial Design (School of Art + Design) . 2Director of the (dis)Ability Design Studio (Beckman Institute) . 3Health Innovation Professor (Carle Illinois College of Medicine)

11:00 - 12:00 PM MEETING

MEMBERSHIP BUSINESS MEETING Calusa EFGH Get involved! Join us for reports from the society leadership on the state and future of the association. All members are welcome and encouraged to attend.

12:00 - 3:00 PM BREAK

FREE TIME Lunch On Own

3:00 - 4:00 PM WORKSHOP

JOURNAL CLUB: HISTORY OF ASSESSING LIGAND SENSITIVITY AND SELECTIVITY OF ODORANT RECEPTORS Great Egret This year’s Journal Club will highlight the evolution of methods utilized to assess the physiological role and function of odorant receptors since their discovery in 1991 by Buck and Axel. We will start by reviewing Zhao et al. ’s 1998 paper, “Functional expression of a mammalian odorant receptor, ” in which the authors accomplished rat I7 receptor expression in its native environment, the olfactory sensory neuron, via recombinant adenovirus. The authors found this receptor is selective for C7 to C10 saturated aliphatic aldehydes although they did not resolve how those odorants physically interact with receptor binding sites. However, this and other expression approaches launched decades of additional work to identify ligands for the family of odorant receptors. While much progress has been made, a recent review by Lalis et al observed that a ligand has not been identified for approximately half of the known receptor variants. Thus, our discussion will include the 2024 paper by de March et al. “Engineered odorant receptors illuminate the basis of odour discrimination, ” and its application of cryo-EM to the long unresolved problem of describing odorant receptors protein structure. This exciting advancement furthers our understanding of the molecular determinants of ligand selectivity and will enable further deorphanization via in silico methodologies. AGENDA Introduction (Jessica H. Brann, Ph. D, dsm-firmenich, New York, NY, USA) Classic publication: Functional expression of a mammalian odorant receptor - PubMed (Ricardo Araneda, Ph. D, University of Maryland, College Park, MD, USA) Recent publication: Engineered odorant receptors illuminate the basis of odour discrimination - PubMed (Mona Marie, Ph. D, Molecular Genetics and Microbiology Department, Duke University School of Medicine, Durham, NC, USA)

4:00 - 6:00 PM POSTER SESSION

POSTER SESSION IV (click to view) (click to close) Estero Ballroom

OLFACTORY DYSFUNCTION

201

UNVEILING THE SULFUR SCENT: THE IMPACT OF COPPER METABOLISM ON OLFACTORY DYSFUNCTION IN WILSON'S DISEASE Shania Appadoo1, Mona Marie1, Maira H. Nagai1, Martina Ralle2, Hiroaki Matsunami1. 1Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA. 2Department of Biochemistry and Molecular Biology, Oregon Health a Science University, Portland, OR, USA

203

PERSISTENT CHEMOSENSORY DYSFUNCTION AFTER COVID-19 AND ITS ASSOCIATIONS WITH QUALITY OF LIFE AND EATING BEHAVIOUR: THE COVORTS STUDY Birgit van Dijk, Sanne Boesveldt. 1Division of Human Nutrition and Health, Wageningen University a Research, Wageningen, Netherlands

205

RELATION BETWEEN OLFACTORY CLEFT FINDINGS AND PH IN OLFACTORY DYSFUNCTION PATIENTS Rumi Sekine1, 2, Eri Mori2, Yuji Kishimoto2, Monami Nagai2, Masayoshi Tei2, 3, HIrotaka Tanaka2, 4, Nobuyoshi Otori2. 11. Department of Otorhinolaryngology, St. Lukers International Hospital, Tokyo, Japan. 22. Department of Otorhinolaryngology, The Jikei University Hospital, Tokyo, Japan. 33. Department of Otorhinolaryngology, The Jikei University Katsushika Medical Center, Tokyo, Japan. 44. Department of Otorhinolaryngology, The Jikei University Kashiwa Hospital, Chiba, Japan

207

SPECIFIC ASSOCIATIONS EXIST BETWEEN OLFACTORY AND COGNITIVE DEFICITS IN ADULTS WITH POST-COVID PERSISTENT OLFACTORY DYSFUNCTION: A SCENT FOR LONG COVID BASELINE ANALYSIS Nicole M Cash1, Mary Clare M Koebel1, Lisa M McTeague1, 2, Bashar Badran1, Aicko Y Schumann1, Thomas W Uhde1, Rodney J Schlosser3, Bernadette M Cortese1. 1Department of Psychiatry and Behavorial Sciences, Medical University of South Carolina, Charleston, SC, USA. 2Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC, USA. 3Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USA

209

MOLECULAR MECHANISMS OF OLFACTORY TRAINING IN DYSOSMIC AND NORMOSMIC INDIVIDUALS Ronja Hopf1, Emely Kruschwitz2, Thomas Hummel2, Dietmar Krautwurst1. 1Leibniz-Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany. 2Department of Otorhinolaryngology, Faculty of Medicine Carl Gustav Carus, Smell a Taste Clinic, Technische Universitat Dresden, Dresden, Germany

211

NORMOSOMIC PATIENTS IN A SMELL AND TASTE CLINIC Antje Welge-Lussen 1, Thomas Hummel2. 1Department of Otorhinolaryngology, University Hospital of Basel, Basel, Switzerland. 2Smell a Taste Clinic, Department of Otorhinolaryngology Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany

213

DEFICITS IN OLFACTORY BEHAVIORS IN MICE AFTER SUBCHRONIC E-CIGARETTE EXPOSURE Sean O'Sullivan1, Janae Gordon1, Saheedat Odetayo1, Kafui Ameko1, Mufaro Chiduza1, Agnes Koodaly1, Ashkon Hazrati1, Michael Ack1, Virginia Murray1, Leyla Aydin1, 2, Tatsuya Ogura1, Weihong Lin1. 1University of Maryland, Baltimore County, Baltimore, MD, USA. 2University of Maryland, College Park, College Park, MD, USA

215

PROBING OLFACTORY FUNCTION WITH THE AROMHA BRAIN HEALTH TEST AND THE BRIEF SMELL IDENTIFICATION TEST (B-SIT) Benoit Jobin1, 2, Hengbin Zhang1, Beyzanur Ergun1, Colin Magdama1, 3, Sean Reineke4, Alefiya Dhilla Albers1, 5, Mark W Albers1, 3. 1Department of Neurology, Massachusetts General Hospital, Boston, MA, USA. 2Department of Psychology, Universite du Quebec a Trois-Rivieres, Trois-Rivieres, QC, Canada. 3Program in Neuroscience, Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA. 4AROMHA Inc, Boston, MA, USA. 5Department of Psychology, Endicott College, Beverly, MA, USA

217

COLOR-MODULATED OLFACTORY TESTING: AN INNOVATIVE TOOL FOR EARLY DETECTION OF COGNITIVE DECLINE Sally Arnhardt1, Kristin Steinebach1, Romy Fuchs1, Tim Diener1, Johannes Kornhuber1, Jessica Freiherr1, 2. 1Department of Psychiatry and Psychotherapy, FAU Erlangen-Nurnberg, Schwabachanlage 6, 91054 Erlangen, Germany. 2Sensory Analytics and Technologies, Fraunhofer Institute for Process Engineering and Packaging IVV, Giggenhauser Str. 35, 85354 Freising, Germany

219

UNIQUE FEATURES OF NASAL AIRWAY AND AIRFLOW IMPROVEMENTS POST-DUPILUMAB: A COMPUTATIONAL INVESTIGATION OF ITS EFFECTIVENESS IN RELIEVING OLFACTORY LOSSES Nidhi Jha, Ahmad Odeh, Zhenxing Wu, Aspen R. Schneller, James Mihalich, Christopher Brooks, Casey Curtis, Monika Craft, Kara Wada, Bradley A. Otto, Kathleen M. Kelly, Kai Zhao. The Ohio State University College of Medicine, Columbus, OH, USA

221

CHRONIC OLFACTORY INFLAMMATION: ITS IMPACT ON THE OLFACTORY EPITHELIUM, OLFACTORY BULB AND BRAIN COGNITIVE FUNCTION Derek Cox, Morning Dove Rose, Kaitlyn Taylor-Cox, Diego Rodriguez-Gil, Russell Brown, Cuihong Jia. Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA

223

LIFE SATISFACTION IN CANCER PATIENTS WITH AND WITHOUT CHEMOSENSORY DYSFUNCTION Victoria Esparza1, Vicente Ramirez 1, Alissa Nolden2, Kara Stromberg 3, Valentina Parma 1. 1Monell Chemical Senses Center, Philadelphia, PA, USA. 2University of Massachusetts Amherst, Amherst, MA, USA. 3Fox Chase Cancer Center, Philadelphia, PA, USA

225

OBJECTIVE ASSESSMENT OF LONG-TERM IMPACT OF COVID-19 ON MULTIPLE SENSORY FUNCTIONS: A PRELIMINARY REPORT Veronica L. Formanek1, Ahmad Odeh1, Christina Smith1, Nidhi Jha1, Junichi Tajino1, Jessica H. Lewis1, Lauren Gastineau1, Shivani Patel1, Songzhu Zhao2, Lai Wei2, Aaron C. Moberly3, Daniel M. Merfeld1, Christopher T. Simons4, Megan J. Kobel5, Kai Zhao1. 1Department of Otolaryngology, Head a Neck Surgery, the Ohio State University Wexner Medical Center, Columbus, OH, USA. 2Department of Biomedical Informatics and Center for Biostatistics, The Ohio State University, Columbus, OH, USA. 3Department of Otolaryngology, Head a Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA. 4Department of Food Science and Technology, the Ohio State University, Columbus, OH, USA. 5Department of Speech, Language, and Hearing Sciences, University of Arizona, Tucson, AZ, USA

227

EXTRACTING SMELL DISORDERS AS EARLY INDICATORS OF NEURODEGENERATIVE DISEASES USING NATURAL LANGUAGE PROCESSING Evan Guerra, Halil Kilicoglu. University of Illinois Urbana-Champaign, Champaign, IL, USA

229

EXAMINING THE EFFECTS OF AIR POLLUTION ON ODOR IDENTIFICATION IN AGING Vicente Ramirez, Valentina Parma. Monell Chemical Senses Center, Philadelphia, PA, USA

231

PRE-INFECTION COVID-19 VACCINATION PROTECTS AGAINST SMELL LOSS Shima T. Moein. Research a Development Division, Sensonics International, Haddon Heights, NJ, USA

233

HIGH PESTICIDE EXPOSURE EVENTS AND OLFACTORY IMPAIRMENT AMONG U. S. FARMERS Shengfang Song1, Brenda L. Plassman2, Yaqun Yuan1, Zhehui Luo1, Julie Fleenor2, Corrine Madsen2, Heather MacDonald2, Scott Davis2, Jayant M. Pinto3, Christine G. Parks4, Jonathan N. Hofmann5, Laura E. Beane Freeman5, Dale P. Sandler4, Honglei Chen1. 1Michigan State University, East Lansing, MI, USA. 2Duke University Medical Center, Durham, NC, USA. 3University of Chicago, Chicago, IL, USA. 4National Institute of Environmental Health Sciences, Durham, NC, USA. 5National Cancer Institute, Rockville, MD, USA

235

SENSORY SENSITIVITIES IN AUTISM SPECTRUM DISORDER: INSIGHTS FROM THE GLASGOW SENSORY QUESTIONNAIRE Isabelle Cullen1, 2, Valentina Parma1, 2, Edward Brodkin1. 1University of Pennsylvania, Philadelphia, PA, USA. 2Monell Chemical Senses Center, Philadelphia, PA, USA

237

LIMITED EFFECTS OF ISOLATED CONGENITAL ANOSMIA ON CEREBRAL WHITE MATTER MORPHOLOGY Anja L. Winter1, Fahimeh Darki1, Johan N. Lundstrom1, 2, 3. 1Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. 2Department of Otorhinolaryngology, Karolinska University Hospital, Stockholm, Sweden. 3Monell Chemical Senses Center, Philadelphia, PA, USA

239

PROGNOSIS OF CHEMOSENSORY RECOVERY AMONG LONG COVID-19 PATIENTS - OBJECTIVE ASSESSMENT AT 3 AND 6 MONTHS FOLLOW-UPS Lauren Gastineau1, Shivani Patel1, Veronica Formanek1, Ahmad Odeh1, Nidhi Jha1, Christopher Simons2, Kai Zhao1. 1Department of Otolaryngology, Head a Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA. 2Department of Food Science and Technology, The Ohio State University, Columbus, OH, USA

241

OLFACTORY SYSTEM ALTERATIONS IN A NOVEL MODEL OF DOPAMINERGIC LOSS BY 6-OHDA INJECTIONS IN ADULT ZEBRAFISH Erika Calvo-Ochoa, Nathaniel Vorhees, Samantha Groenwold, Lexus Putt, Nereyda Sanchez-Gama, Mackenzie Williams. Biology Department and Neuroscience Program, Hope College, Holland, MI, USA

DEVELOPMENT/REGENERATION

243

HUMAN OLFACTORY ORGANOIDS AS AN IN VITRO MODEL OF THE OLFACTORY EPITHELIUM Kang-Hoon Kim1, Ankit Chauhan2, Noam Cohen1, 2, 3, Danielle Reed1, Peihua Jiang1, Hong Wang1, Jennifer E Douglas1, 2. 1Monell Chemical Senses Center, Philadelphia, PA, USA. 2University of Pennsylvania, Department of Otorhinolaryngology - Head a Neck Surgery, Philadelphia, PA, USA. 3Philadelphia Veterans Affairs Medical Center Surgical Services, Philadelphia, PA, USA

CORTEX

245

CHARACTERIZING OLFACTORY BRAIN RESPONSES IN YOUNG INFANTS Laura Shanahan1, Leena Mithal2, Marci Messina3, Emma Office2, Lauren Wakschlag2, Patrick Seed2, Thorsten Kahnt4. 1Rhodes College, Memphis, TN, USA. 2Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. 3Northwestern Memorial Hospital, Chicago, IL, USA. 4National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, USA

247

PREMOTOR INPUTS MODULATE PREPARATORY ACTIVITY IN THE GUSTATORY CORTEX John Chen1, 2, Alfredo Fontanini1, 2. 1Program in Neuroscience, Stony Brook, NY, USA. 2Department of Neurobiology and Behavior, Stony Brook, NY, USA

249

MODULATION OF UNIMODAL AND MULTIMODAL SIGNALS IN THE GUSTATORY CORTEX BY POSTERIOR PIRIFORM CORTEX PHOTOSUPPRESSION Caitlin J. White, Chad L. Samuelsen. University of Louisville, Louisville, KY, USA

251

OPTOGENETIC STIMULATION IN THE GUSTATORY CORTEX MIMICS TASTE INPUT PATTERNS Isabella B Allar, Joost X Maier. Wake Forest School of Medicine, Winston-Salem, NC, USA

253

GUSTATORY-OLFACTORY CORTICAL INTERACTIONS IN RESPONSE TO MULTIMODAL STIMULI Thomas R. Gray, Ainsley E. Craddock, Amelia S. White, Isaac Goldstein, Donald B. Katz. Brandeis University, Waltham, MA, USA

255

A COMPARISON OF CORTICAL TASTE REPRESENTATIONS ARISING FROM FREE LICKING AND INTRAORAL DELIVERY Martin Raymond, Jian-You Lin, Donald Katz. Brandeis University, Waltham, MA, USA

257

INHIBITORY PLASTICITY CONTROLS GUSTATORY CORTICAL CIRCUIT REFINEMENT IN THE POSTNATAL PERIOD Hillary C Schiff1, Arianna Maffei2. 1Ohio State University College of Dentistry, Columbus, OH, USA. 2Stony Brook University Department of Neurobiology a Behavior, Stony Brook, NY, USA

259

INTEGRATION OF APPETITIVE FEATURES IN THE ORBITOFRONTAL CORTEX DURING FOOD-BASED CHOICES Matthew P. H. Gardner1, Evan E Hart2, Thomas Stalnaker3, Geoffrey Schoenbaum3, 4, 5. 1Concordia University, Montreal, QC, Canada. 2University of Maryland College Park, College Park, MD, USA. 3National Institute on Drug Abuse, Baltimore, MD, USA. 4Johns Hopkins University, Baltimore, MD, USA. 5University of Maryland School of Medicine, Baltimore, MD, USA

261

INVESTIGATING INTRA-STATE DYNAMICS IN TASTE-EVOKED GUSTATORY CORTEX RESPONSES IN RATS Vincent Calia-Bogan1, Abuzar Mahmood1, Donald Katz1, 2. 1Department of Psychology, Brandeis University, Waltham, MA, USA. 2Volen National Center for Complex Systems, Brandeis University, Waltham, MA, USA

263

OLFACTORY MODULATION OF THE MEDIAL PREFRONTAL CORTEX CIRCUITRY: CONTRIBUTION TO SOCIAL BEHAVIOR IN MICE Janardhan P. Bhattarai1, Yingqi Wang1, Yun-Feng Zhang1, Brittany Chapman1, Abby Lieberman1, Omer Zeliger1, Krishna Jaladanki1, David Kedeme1, Atsushi Kamiya2, Wenqin Luo1, Minghong Ma1. 1Department of Neuroscience, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. 2Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA

265

ANATOMICAL AND PHYSIOLOGICAL CHARATERIZATION OF LONG RANGE PATHWAYS FROM HIPPOCAMPUS TO ANTERIOR OLFACTORY NUCLEUS Cosar Uzun, Meigeng Hu, Alexander Kershaw, Yaping Li, Shaolin Liu. Center for Neurological Disease Research, Department of Physiology a Pharmacology, Department of Biomedical Science, University of Georgia, Athens, GA, USA

DEVELOPMENT/REGENERATION

267

ASSESSING RETRONASAL SMELL PERCEPTION IN YOUNG CHILDREN USING A PICTORIAL RATING SCALE AND FACIAL ACTION CODING Sarah Colbert1, Gaby de la Vega1, Madison Patel2, Joost Maier1. 1Wake Forest University School of Medicine, Winston-Salem, NC, USA. 2Wake Forest University, Winston-Salem, NC, USA

269

ESSENTIAL ROLES OF HEDGEHOG ANTAGONIST HHIP IN FILIFORM PAPILLAE DEVELOPMENT Gabrielle C. Audu1, Greg Holmes2, Archana Kumari1. 1Rowan-Virtua School of Osteopathic Medicine, Stratford, NJ, USA. 2Icahn School of Medicine at Mount Sinai, New York, NY, USA

271

UMAMI TASTE DETECTION IN CHILDREN VERSUS ADULTS Claudia M. Asensio1, Jessica G. Nicanor Carreon 1, Julie A. Mennella2, M. Yanina Pepino1. 1University of Illinois Urbana-Champaign, Urbana, IL, USA. 2Monell Chemical Senses Center, Philadelphia, PA, USA

273

LONGER IN-UTERO DEVELOPMENT LEADS TO ENHANCED FUNCTIONAL CONNECTIVITY AND POSTNATAL EXPERIENCE-DEPENDENT REFINEMENT OF THE OLFACTORY NETWORK Johan N. Lundstrom1, 2, 3, Peter Fransson1, Fahimeh Darki1. 1Karolinska Institutet, Stockholm, Sweden. 2Karolinska University Hospital, Stockholm, Sweden. 3Monell Chemical Senses Center, Philadelphia, PA, USA

275

MOLECULAR MECHANISMS SHAPING TASTE RECEPTOR DIFFERENTIATION IN SWEET AND BITTER RECEPTOR LINEAGES Kaitao Zhao1, Thirada Boonrawd2, Yue Yu2, Hojoon Lee2, Kevin Monahan1. 1Rutgers University, Piscataway, NJ, USA. 2Northwestern University, Evanston, IL, USA

277

REGENERATIVE POTENTIAL OF CANNABIDIOL IN CHEMICALLY-ABLATED OLFACTORY EPITHELIUM Bridger Menlove1, 2, Olivia C. Turner2, Chloe Crespi2, Madison Klick2, Debra A. Fadool1, 2, 3. 1Program in Neuroscience The Florida State University, Tallahassee, FL, USA. 2Department of Biology The Florida State University, Tallahassee, FL, USA. 3Institute of Molecular Biophysics The Florida State University, Tallahassee, FL, USA

279

THE ROLE OF CHROMATIN STRUCTURE IN REGULATING VOMERONASAL RECEPTOR EXPRESSION Kevin Monahan, Jerome Kahiapo, Nader Boutros Ghali. Rutgers University, Department of Molecular Biology and Biochemistry, Piscataway, NJ, USA

281

THE IMPACT OF MATERNAL HIGH FAT AND HIGH SACCHARIN DIET ON OFFSPRING TASTE PROCESSING Katherine Headley , Elsa Shaikh, Veronica L. Flores. Furman University, Greenville, SC, USA

DISCRIMINATION

283

BEHAVIORAL RESPONSES TO CAFFEINE ARE NOT THE SAME AS THOSE WE SEE TO OTHER BITTERS. Emily Demieri1, Verenice Ascencio Gutierrez1, Tiago Mortellaro1, Ann-Marie Torregrossa1, 2. 1University at Buffalo (Department of Psychology), Buffalo, NY, USA. 2University at Buffalo (Center for Ingestive Behavior), Buffalo, NY, USA

285

NON-MONOTONIC PSYCHOMETRIC FUNCTIONS FOR PHENYL ETHYL ALCOHOL. E. Leslie Cameron1, Natalie Scalamera1, Brooke Bastian1, Shima T. Moein2, Richard L. Doty3. 1Carthage College, Kenosha, WI, USA. 2Sensonics International, Haddon Heights, NJ, USA. 3University of Pennsylvania, Philadelphia, PA, USA

287

IMPROVING OLFACTORY SENSITIVITY DETECTION USING TREESCLASSIFICATION Prasanna Karunanayaka2, Pemantha Lakraj1, Senal Peiris2. 1Department of Statistics, University of Colombo, Colombo, Sri Lanka. 2Department of Radiology, Penn State University College of Medicine, Hershey, PA, USA

289

IDENTIFYING SETS OF PRIMARY ODORS TO MATCH TARGET SCENTS Elizabeth Hamel1, Robert Pellegrino1, Jennifer Margolis1, Carissa Evans1, Marissa Kamarck1, Emily Mayhew2, Joel Mainland1, 3. 1Monell Chemical Senses Center, Philadelphia, PA, USA. 2Michigan State University, East Lansing, MI, USA. 3University of Pennsylvania, Philadelphia, PA, USA

7:00 - 9:00 PM LECTURE

AWARD LECTURES Chair/Organizer: Yanina Pepino Calusa EFGH