ACHEMS 2025
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SPLTRAK Abstract Submission
Poster #Learning & Memory
Invited Symposium: Encoding odor value - where the olfactory and reward system meet
Wolfgang Kelsch2,3 & Sarah Sniffen1
1Departments of Neuroscience and Pharmacology & Therapeutics, Florida Chemical Senses Institute, University of Florida College of Medicine, Gainesville, FL, United States
2Central Institute of Mental Health, Heidelberg University, Mannheim, --, Germany
3Johannes-Gutenberg University Mainz, Mainz, --, Germany

How do odors acquire value? The answer to this question lies in brain regions that integrate olfactory information and hedonic value. The olfactory tubercle, also known as the tubular striatum, was originally classified as an olfactory cortical structure with direct input from the olfactory bulb. However, over the last decade, exciting progress has advanced our understanding of the tubercle as a key region of the mesolimbic system integrating chemosensory information into value processing. These discoveries have inspired this first AChemS symposium dedicated to the olfactory tubercle. This symposium will address i) new insight into the tubercle's role in the coding of both odor identity and odor value, ii) its involvement in hedonic processing in rodents and humans, and iii) the neural circuits underlying its influence on behavior. Overall, these findings emphasize the special role of the olfactory tubercle in the integration of both odor identity and hedonic value and position it as a central hub for orchestrating odor-driven behavior.