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| Poster #252 Human olfactory bulb beta activity predicts the gamma activity of the following sniff |
| Frans Nordén1, Behzad Iravani1, Anja L. Winter1, Mikael Lundqvist1, Artin Arshamian1, Johan N. Lundström1,2,3 1Karolinska Institutet, Solna, --, Sweden 2Monell Chemical Senses Center, Philadelphia, PA, United States 3Stockholm University Brain Center, Stockholm, --, Sweden |
Between the human olfactory bulb (OB) and the piriform cortex (PC), gamma and beta bands have been shown to communicate odor identity, valence, and intensity. Early gamma activity is directed from the OB to the PC, while later beta activity has been shown to carry information communicated back from the PC to the OB. We hypothesized that the feedback conveyed through the beta band informs the gamma band in the OB with information regarding the just experienced odor to influence processing of the following sniff. To evaluate this, we conducted a study with 40 participants where odor delivery was initiated at the beginning of the first sniff and remained until one second after the second sniff. Neural recordings were collected using EEG and source reconstruction was employed to extract the neural time course in the OB. We related the power spectrum of the beta band activity in the OB during the first sniff to gamma band activity during the second sniff through a mixed-effects model, controlling for baseline beta activity. The results show that stronger beta power during the first sniff predicts stronger gamma power during the second sniff. This suggests a connection between beta activity in the first sniff and gamma activity in the second sniff. |