Presentation Details
| Fluid Balance Revisited: Oral, Postoral, and Central Signals Driving Water Intake Derek Daniels. Department of Biological Sciences and the Center for Ingestive Behavior Research, University at Buffalo, SUNY, Buffalo, NY, USA |
Abstract
Discussions of appetition have largely focused on food intake, although a significant amount of research on the topic has provided 'food' in fluid form. Although presenting 'food' in liquid form is common and often necessary, the large amount of water consumed as the vehicle for the food creates a potential confounding variable. For this and other reasons, it is important to ask if the concept of appetition can be extended to include thirst and water intake. ‘Appetition,’ however, is used inconsistently as a term, making it challenging to determine if its application to fluid intake is ever appropriate. On one hand, the term is used to refer to feedback from the gut that acts to increase the size of a meal. In this sense, the focus on the gut likely makes the term inapplicable to water consumption. If, on the other hand, the specificity of the gut is less important to the overall concept, and appetition also encompasses signals from the oral cavity that promote intake, then findings from our laboratory and from others showing sensitized responses to dipsogens fit into the appetition framework. In this sense, water intake sensitization also could serve as a new model of appetition, with a yet to be discovered neural or hormonal signals mediating the response. A discussion of these issues, as well as a description of the findings related to sensitization of water intake, will be presented.
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No part of this publication may be reproduced, distributed, or transmitted in any form or by any means, including photocopying, recording, or other electronic or mechanical methods, without the prior written permission of the author.